Chen Andrew, Shahiyan Robert H, Anger Jennifer T
Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
Sex Med Rev. 2022 Jan;10(1):71-76. doi: 10.1016/j.sxmr.2020.12.005. Epub 2021 Jul 1.
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition with highly prevalent negative consequences on sexual health and quality of life. However, there is a lack of consensus regarding treatment options that improve sexual function in this population. This study aims to review the current literature on sexual health outcomes in patients treated for IC/BPS.
We conducted a systematic review of the literature on sexual health outcomes after treatment of IC/BPS. PubMed, MEDLINE, EMBASE, CINHAL, and Google Scholar were queried, and results were screened using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Inclusion criteria for this review were: IC/BPS was clearly defined in the cohort, sexual health outcomes were measured as the primary or a secondary outcome, manuscript was written in English from January 2000 to April 2020. Studies on cystectomy were excluded as radical surgery is a confounding factor for sexual dysfunction.
We identified 1611 items with our search algorithm and determined that 10 studies ultimately met inclusion criteria. 4 of 10 studies reported improved sexual function after treatment. 4 of 10 studies were randomized control trials and reported no improvement in sexual function in each of the therapies that were investigated. Data were conflicting regarding the effect of intravesical hyaluronic acid.
This systematic review demonstrates the lack of focus on sexual health outcomes in studies of the IC/BPS. There was no strong evidence that any modality used to treat IC/BPS also improves sexual function despite the higher prevalence in this population. Chen A, Shahiyan RH, Anger J. Interstitial Cystitis/Bladder Pain Syndrome Treatment: A Systematic Review of Sexual Health Outcomes. Sex Med Rev 2022;10:71-76.
间质性膀胱炎/膀胱疼痛综合征（IC/BPS）是一种慢性疾病，对性健康和生活质量有高度普遍的负面影响。然而，对于改善该人群性功能的治疗方案，目前尚无共识。本研究旨在回顾关于接受IC/BPS治疗患者性健康结局的现有文献。
我们对IC/BPS治疗后性健康结局的文献进行了系统回顾。检索了PubMed、MEDLINE、EMBASE、CINHAL和谷歌学术，并使用系统评价和Meta分析的首选报告项目（PRISMA）指南筛选结果。本综述的纳入标准为：队列中明确界定了IC/BPS，性健康结局作为主要或次要结局进行测量，2000年1月至2020年4月期间以英文撰写的手稿。由于根治性手术是性功能障碍的一个混杂因素，因此排除了膀胱切除术的研究。
我们通过搜索算法识别出1611项内容，并确定最终有10项研究符合纳入标准。10项研究中有4项报告治疗后性功能有所改善。10项研究中有4项是随机对照试验，报告所研究的每种疗法的性功能均无改善。关于膀胱内注射透明质酸的效果，数据存在冲突。
本系统评价表明，IC/BPS研究中缺乏对性健康结局的关注。尽管该人群中患病率较高，但没有强有力的证据表明用于治疗IC/BPS的任何方式也能改善性功能。陈A、沙希扬RH、安格尔J。间质性膀胱炎/膀胱疼痛综合征治疗：性健康结局的系统评价。性医学评论2022；10：71 - 76。
