Arch Intern Med. 1988 Jan;148(1):36-69.
This report of an expert panel of the National Cholesterol Education Program provides new guidelines for the treatment of high blood cholesterol in adults 20 years of age and over. Total cholesterol levels are classified as follows: less than 200 mg/dL--"desirable blood cholesterol"; 200 to 239 mg/dL--borderline-high blood cholesterol; greater than or equal to 240 mg/dL--high blood cholesterol. The guidelines detail which patients should go on to have lipoprotein analysis, and which should receive cholesterol-lowering treatment on the basis of their low density lipoprotein (LDL)-cholesterol levels and status with respect to other coronary heart disease risk factors. Dietary therapy is the primary cholesterol-lowering treatment. The report specifies the LDL-cholesterol levels at which dietary therapy should be started and the goals of therapy, and provides detailed guidance on the nature of the recommended dietary changes. If, after six months of intensive dietary therapy, LDL-cholesterol exceeds specified levels, drug treatment should be considered.
美国国家胆固醇教育计划专家小组的这份报告为20岁及以上成年人的高血胆固醇治疗提供了新指南。总胆固醇水平分类如下:低于200毫克/分升——“理想血胆固醇”;200至239毫克/分升——临界高血胆固醇;大于或等于240毫克/分升——高血胆固醇。该指南详细说明了哪些患者应进一步进行脂蛋白分析,以及哪些患者应根据其低密度脂蛋白(LDL)胆固醇水平和其他冠心病危险因素状况接受降胆固醇治疗。饮食疗法是主要的降胆固醇治疗方法。该报告规定了应开始饮食疗法的LDL胆固醇水平和治疗目标,并就推荐饮食改变的性质提供了详细指导。如果经过六个月的强化饮食疗法后,LDL胆固醇超过规定水平,则应考虑药物治疗。