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基于单模体设置的多定位引导系统的计划精简质量保证的开发与纵向分析

Development and Longitudinal Analysis of Plan-Based Streamlined Quality Assurance on Multiple Positioning Guidance Systems With Single Phantom Setup.

作者信息

Zhou Shun, Li Junyu, Du Yi, Yu Songmao, Wang Meijiao, Wu Hao, Yue Haizhen

机构信息

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital & Institute, Beijing, China.

Institute of Medical Technology, Peking University Health Science Center, Beijing, China.

出版信息

Front Oncol. 2021 Jun 16;11:683733. doi: 10.3389/fonc.2021.683733. eCollection 2021.

Abstract

PURPOSE

This study was to propose and validate an efficient and streamlined quality assurance (QA) method with a single phantom setup to check performances of patient positioning guidance systems including six-degree-of-freedom (6DoF) couch, X-ray modalities (kV-kV, MV-MV and CBCT), optical surface imaging system (AlignRT), lasers and optical distance indicator (ODI).

METHODS AND MATERIALS

The QA method was based on a pseudo-patient treatment plan using the AlignRT cube phantom. The cube was first randomly set up on the couch, and the initial position offsets were acquired by AlignRT and CBCT. The cube was restored to its reference position by 6DoF couch shift, during which the couch motion accuracy and tracking performances of AlignRT and CBCT were derived. After that, the residual offsets were acquired by kV-kV, MV-MV and AlignRT to derive the isocenter discrepancies. Finally, the laser alignment and ODI values were visually inspected. The QA procedure had been internally approved as a standard weekly QA test, and the results over 50 weeks were longitudinally analyzed for clinical validation.

RESULTS

The 6DoF couch motion errors as well as the tracking errors of AlignRT were sub-millimeter and sub-degree, and no deviation over 1 mm or 1 deg was identified. The ROI mode of isocenter (ISO) in AlignRT exhibited more consistent results than the centroid (CEN). While the isocenter discrepancy between CBCT and kV-kV was negligible, the maximal discrepancies between CBCT and MV-MV were 0.4 mm in LNG and 0.3 deg in PITCH. The isocenter discrepancies between CBCT and AlignRT were <0.5 mm in translation and <0.3 deg in rotation. For AlignRT, the isocenter discrepancies between the DICOM and SGRT references were about 0.6 mm in VRT, 0.5 mm in LNG and 0.2 deg in PITCH. As the therapists became familiar with the workflow, the average time to complete the whole procedure was around 23 min.

CONCLUSIONS

The streamlined QA exhibits desirable practicality as an efficient multipurpose performance check on positioning guidance systems. The stability, tracking performance and isocenter congruence of the positioning guidance systems have been fully validated for all clinical image guidance RT application, even SRS/SBRT, which requires the strictest tolerance.

摘要

目的

本研究旨在提出并验证一种高效且简化的质量保证(QA)方法,该方法采用单一体模设置来检查患者定位引导系统的性能,这些系统包括六自由度(6DoF)治疗床、X射线模态(kV-kV、MV-MV和CBCT)、光学表面成像系统(AlignRT)、激光和光学距离指示器(ODI)。

方法和材料

QA方法基于使用AlignRT立方体体模的伪患者治疗计划。首先将立方体随机放置在治疗床上,通过AlignRT和CBCT获取初始位置偏移。通过6DoF治疗床移位将立方体恢复到其参考位置,在此过程中得出治疗床的运动精度以及AlignRT和CBCT的跟踪性能。之后,通过kV-kV、MV-MV和AlignRT获取残余偏移以得出等中心差异。最后,目视检查激光对准和ODI值。QA程序已在内部被批准为标准的每周QA测试,并对50周以上的结果进行纵向分析以进行临床验证。

结果

6DoF治疗床的运动误差以及AlignRT的跟踪误差均在亚毫米和亚度级别,未发现超过1毫米或1度的偏差。AlignRT中等中心(ISO)的ROI模式比质心(CEN)表现出更一致的结果。虽然CBCT和kV-kV之间的等中心差异可忽略不计,但CBCT和MV-MV之间在LNG方向的最大差异为0.4毫米,在PITCH方向为0.3度。CBCT和AlignRT之间的等中心差异在平移方向上<0.5毫米,在旋转方向上<0.3度。对于AlignRT,DICOM和SGRT参考之间的等中心差异在VRT方向约为0.6毫米,在LNG方向为0.5毫米,在PITCH方向为0.2度。随着治疗师熟悉工作流程,完成整个过程的平均时间约为23分钟。

结论

简化后的QA作为一种对定位引导系统的高效多用途性能检查,具有理想的实用性。定位引导系统的稳定性、跟踪性能和等中心一致性已针对所有临床图像引导放疗应用,甚至是要求最严格容差的立体定向放射治疗(SRS)/立体定向体部放射治疗(SBRT),进行了充分验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdcd/8242243/e886b08ea562/fonc-11-683733-g001.jpg

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