Department of Life Sciences, Dibrugarh University, Dibrugarh 786004, Assam, India.
Department of Microbiology, Jorhat Medical College, Jorhat 785001, Assam, India.
J Mycol Med. 2021 Sep;31(3):101167. doi: 10.1016/j.mycmed.2021.101167. Epub 2021 Jun 19.
Lasiodiplodia theobromae is a dematiaceous non-dermatophyte mold (NDM), rarely reported to cause onychomycosis. Here, we report three cases of toenail onychomycosis caused by L. theobromae in agricultural workers. Two patients presented with total dystrophic onychomycosis and one with distal and lateral subungual onychomycosis. These cases have unique importance that besides traumatized nail infection, its rarity has adversely affected the agricultural workers livelihood as L. theobromae sporulates poorly, resistant to commonly used antifungal therapy. From the literature search, we assume that this is the first case series of onychomycosis caused by L. theobromae from a tropical country like India.
热带国家(如印度)罕见报道的申克孢子丝菌引起的趾甲真菌病。这里,我们报告了三例农业工作者患由拉氏拟青霉引起的趾甲真菌病。两例患者表现为全营养不良性甲真菌病,一例表现为远端和侧位甲下真菌病。这些病例具有独特的重要性,除了创伤性指甲感染外,其罕见性也对农业工作者的生计产生了不利影响,因为拉氏拟青霉产孢能力差,对常用抗真菌治疗有耐药性。从文献检索中,我们假设这是印度等热带国家首例由拉氏拟青霉引起的甲真菌病病例系列。