Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-Nishi, 889-2192, Miyazaki, Japan.
Vietnam National University of Agriculture, Gia Lam, Hanoi, Vietnam.
BMC Vet Res. 2021 Jul 5;17(1):235. doi: 10.1186/s12917-021-02941-7.
Porcine epidemic diarrhoea (PED) is a highly contagious infectious disease with negative economic impacts on the swine industry. PED outbreaks were reported from 2009 to 2015, but sporadic infection has been observed until now in Vietnam. However, the seroprevalence of PEDV infection has not yet been reported for commercial pig farms in Vietnam. The aim of this study was to assess the seroprevalence of PEDV infection in Vietnamese pig farms to reveal the endemic status of PEDV in northern Vietnam.
A serological survey of PEDV infection was carried out using indirect ELISA in commercial pig farms in Hai Duong, Hung Yen and Thai Binh provinces in northern Vietnam in 2019. Twenty sera were randomly collected from each of 10 commercial pig farms, from each province; none of the farms had vaccinated for PEDV. Serological evidence of natural PEDV infection, expressed as a high antibody titre, was observed in the pig farms in all 3 provinces. The OD values were significantly higher (p < 0.001) for pig sera from Thai Binh than from Hai Duong and Hung Yen. No significant differences (p > 0.05) were detected for seropositivity to PEDV based on locality, age, pig breed and farm size.
This study indicates serological evidence of natural PEDV infection with high antibody titre in commercial pig farms. PEDV infection was widespread among the pig population in these 3 provinces and that good management and strict biosecurity are needed at these pig farms.
猪流行性腹泻（PED）是一种具有高度传染性的传染病，对养猪业造成了负面影响。PED 疫情于 2009 年至 2015 年期间报告，但在越南至今仍观察到零星感染。然而，尚未报道越南商业猪场的 PEDV 感染血清阳性率。本研究旨在评估越南商业猪场中 PEDV 感染的血清阳性率，以揭示 PEDV 在越南北部的流行状况。
2019 年在越南北部的海阳、永福和太平省的商业猪场进行了 PEDV 感染的血清学调查，使用间接 ELISA 进行。从每个省的 10 个商业猪场中随机抽取 20 份血清；所有猪场均未接种 PEDV 疫苗。在所有 3 个省份的猪场中，均观察到自然 PEDV 感染的血清学证据，表现为高抗体滴度。来自太平省的猪血清的 OD 值明显高于海阳省和永福省（p<0.001）。基于地理位置、年龄、猪品种和猪场规模，PEDV 血清阳性率无显著差异（p>0.05）。
本研究表明，商业猪场存在 PEDV 感染的血清学证据，且抗体滴度较高。这 3 个省的猪群中 PEDV 感染广泛存在，这些猪场需要良好的管理和严格的生物安全措施。
