Department of Pediatric Surgery, Pediatric Urology Unit, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain.
Scand J Urol. 2021 Aug;55(4):307-312. doi: 10.1080/21681805.2021.1948098. Epub 2021 Jul 6.
The aim of the study was to compare 3 mm mini-laparoscopy (mini LP), standard 5 mm laparoscopy (LP) and open surgery for pediatric pyeloplasty in a single center.
Patients who underwent pyeloplasty from 1997 to 2017 at Hospital Sant Joan de Déu were prospectively collected. Demographic data, clinical, surgical and radiological variables were assessed. A multivariate logistic regression analysis was performed in order to identify risks for surgical complications, urinary leak and need for redo-surgery.
340 pyeloplasties were performed in this period: 197 open, 30 LP and 113 mini LP. Independent risk factors for surgical complications in a multivariate logistic regression model were: LP (vs mini LP, OR = 3.95; 95% CI: 1.13-13.8), higher differential renal function (each point more increases the risk 6%; 95% CI: 1-11%), older children (every year increases the risk 1.11 times; 95% CI: 1.002-1.225). Open surgery, pelvis diameter or the use of different stents were not risk factors. This model had an 80% PPV and a 92% NPV. LP (OR = 4.65; 95% CI: 1.08-19.96) and longer surgical time (OR = 1.014; 95% CI: 1.003-1.025) were independent risk factors for urinary leak. Higher pelvis diameter (OR = 0.93; 95% CI: 0.87-0.99) and the use of external stents were independent protective risk factors for urinary leak (OR = 0.09; 95% CI: 0.01-0.72). We have not found independent risk factors for redo-surgery in a multivariate logistic regression model.
mini LP can be safely and effectively used to perform pyeloplasty in pediatric patients of all ages.
本研究旨在比较单中心 3mm 迷你腹腔镜(mini LP)、标准 5mm 腹腔镜(LP)和开放手术治疗小儿肾盂成形术的效果。
前瞻性收集 1997 年至 2017 年在圣若翰保禄医院接受肾盂成形术的患者。评估人口统计学数据、临床、手术和影像学变量。进行多变量逻辑回归分析,以确定手术并发症、尿漏和再次手术的风险因素。
在此期间共进行了 340 例肾盂成形术:197 例开放手术、30 例 LP 和 113 例 mini LP。多变量逻辑回归模型中手术并发症的独立危险因素是:LP(与 mini LP 相比,OR=3.95;95%CI:1.13-13.8)、更高的分肾功能(每增加 1 个点,风险增加 6%;95%CI:1-11%)、较大的儿童(每增加 1 岁,风险增加 1.11 倍;95%CI:1.002-1.225)。开放手术、肾盂直径或不同支架的使用不是危险因素。该模型的 PPV 为 80%,NPV 为 92%。LP(OR=4.65;95%CI:1.08-19.96)和较长的手术时间(OR=1.014;95%CI:1.003-1.025)是尿漏的独立危险因素。较高的肾盂直径(OR=0.93;95%CI:0.87-0.99)和使用外部支架是尿漏的独立保护因素(OR=0.09;95%CI:0.01-0.72)。我们没有在多变量逻辑回归模型中发现再次手术的独立危险因素。
mini LP 可安全有效地用于治疗所有年龄段的小儿患者的肾盂成形术。