• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

COVID-19 in children: acute endotheliopathy, but forgotten prostacyclin replacement?

作者信息

Schranz Dietmar

机构信息

Johann-Wolfgang-Goethe University Clinic, Frankfurt, Germany.

出版信息

Cardiol Young. 2022 Apr;32(4):572-573. doi: 10.1017/S1047951121002626. Epub 2021 Jun 21.

DOI:10.1017/S1047951121002626
PMID:34227929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8267333/
Abstract
摘要

相似文献

1
COVID-19 in children: acute endotheliopathy, but forgotten prostacyclin replacement?儿童新冠病毒感染：急性内皮病变，但前列环素替代治疗被遗忘了？
Cardiol Young. 2022 Apr;32(4):572-573. doi: 10.1017/S1047951121002626. Epub 2021 Jun 21.
2
Efficacy and safety of a 72-h infusion of prostacyclin (1 ng/kg/min) in mechanically ventilated patients with pulmonary infection and endotheliopathy-protocol for the multicenter randomized, placebo-controlled, blinded, investigator-initiated COMBAT-ARF trial.前列环素（1纳克/千克/分钟）持续72小时输注在机械通气的肺部感染和内皮病变患者中的疗效和安全性——多中心随机、安慰剂对照、双盲、研究者发起的COMBAT-ARF试验方案
Acta Anaesthesiol Scand. 2025 Jan;69(1):e14565. doi: 10.1111/aas.14565.
3
Prostacyclin in Intubated Patients with COVID-19 and Severe Endotheliopathy: A Multicenter, Randomized Clinical Trial.COVID-19 伴严重内皮病变插管患者应用前列环素：一项多中心、随机临床试验。
Am J Respir Crit Care Med. 2022 Feb 1;205(3):324-329. doi: 10.1164/rccm.202108-1855OC.
4
The effect of prostacyclin infusion on markers of endothelial activation and damage in mechanically ventilated patients with SARS-CoV-2 infection.前列腺素输注对机械通气的 SARS-CoV-2 感染患者内皮激活和损伤标志物的影响。
J Crit Care. 2022 Jun;69:154010. doi: 10.1016/j.jcrc.2022.154010. Epub 2022 Feb 17.
5
Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation.血小板病和血管内皮病：COVID-19 血栓炎症的重要促成因素。
Nat Rev Cardiol. 2021 Mar;18(3):194-209. doi: 10.1038/s41569-020-00469-1. Epub 2020 Nov 19.
6
Epoprostenol (Prostacyclin Analog) as a Sole Anticoagulant in Continuous Renal Replacement Therapy for Critically Ill Children With Liver Disease: Single-Center Retrospective Study, 2010-2019: Erratum.依前列醇（前列环素类似物）作为肝病重症患儿持续肾脏替代治疗中的单一抗凝剂：单中心回顾性研究，2010 - 2019年：勘误
Pediatr Crit Care Med. 2024 Mar 1;25(3):e175. doi: 10.1097/PCC.0000000000003472. Epub 2024 Mar 4.
7
The coagulopathy, endotheliopathy, and vasculitis of COVID-19.COVID-19 的凝血功能障碍、血管内皮功能障碍和血管炎。
Inflamm Res. 2020 Dec;69(12):1181-1189. doi: 10.1007/s00011-020-01401-6. Epub 2020 Sep 12.
8
Insights into Endotheliopathy in COVID-19.对新冠病毒病中内皮病变的见解
Am J Respir Crit Care Med. 2022 Oct 15;206(8):926-928. doi: 10.1164/rccm.202207-1258ED.
9
COVID-19-associated Lung Microvascular Endotheliopathy: A "From the Bench" Perspective.COVID-19 相关肺微血管内皮病变：从基础研究角度看。
Am J Respir Crit Care Med. 2022 Oct 15;206(8):961-972. doi: 10.1164/rccm.202107-1774OC.
10
Acute Kidney Injury and Special Considerations during Renal Replacement Therapy in Children with Coronavirus Disease-19: Perspective from the Critical Care Nephrology Section of the European Society of Paediatric and Neonatal Intensive Care.儿童 2019 冠状病毒病急性肾损伤及肾脏替代治疗的特殊考虑：来自欧洲儿童和新生儿重症监护学会重症肾脏病学组的观点。
Blood Purif. 2021;50(2):150-160. doi: 10.1159/000509677. Epub 2020 Jul 14.

引用本文的文献

1
Myocardial Infarction in Children after COVID-19 and Risk Factors for Thrombosis.新冠病毒感染后儿童的心肌梗死及血栓形成的危险因素
Diagnostics (Basel). 2022 Apr 1;12(4):884. doi: 10.3390/diagnostics12040884.

本文引用的文献

1
SARS-CoV-2 B.1.1.7 and B.1.351 spike variants bind human ACE2 with increased affinity.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的B.1.1.7和B.1.351刺突变异体与人类血管紧张素转换酶2（ACE2）的结合亲和力增强。
Lancet Infect Dis. 2021 Aug;21(8):1070. doi: 10.1016/S1473-3099(21)00262-0. Epub 2021 May 19.
2
COVID-19 FAQs in paediatric and congenital cardiology: AEPC position paper.儿童和先天性心脏病 COVID-19 常见问题解答：AEPC 立场文件。
Cardiol Young. 2021 Mar;31(3):344-351. doi: 10.1017/S1047951120005028. Epub 2021 Jan 7.
3
Cytokine Storm.细胞因子风暴
N Engl J Med. 2020 Dec 3;383(23):2255-2273. doi: 10.1056/NEJMra2026131.
4
The endothelium as Achilles' heel in COVID-19 patients.内皮细胞——新冠患者的致命弱点
Cardiovasc Res. 2020 Dec 1;116(14):e195-e197. doi: 10.1093/cvr/cvaa327.
5
Potential Therapeutic Options for COVID-19: Current Status, Challenges, and Future Perspectives.2019冠状病毒病的潜在治疗选择：现状、挑战及未来展望
Front Pharmacol. 2020 Sep 15;11:572870. doi: 10.3389/fphar.2020.572870. eCollection 2020.
6
Toll-like receptors and COVID-19: a two-faced story with an exciting ending.Toll样受体与新型冠状病毒肺炎：一个有着激动人心结局的双面故事。
Future Sci OA. 2020 Jul 30;6(8):FSO605. doi: 10.2144/fsoa-2020-0091.
7
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study.英国因 COVID-19 住院的儿童和青少年的临床特征：前瞻性多中心观察队列研究。
BMJ. 2020 Aug 27;370:m3249. doi: 10.1136/bmj.m3249.
8
Severe COVID-19 Is a Microvascular Disease.重症新型冠状病毒肺炎是一种微血管疾病。
Circulation. 2020 Oct 27;142(17):1609-1611. doi: 10.1161/CIRCULATIONAHA.120.050354. Epub 2020 Sep 2.
9
The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial.前列腺素（依洛前列素）输注剂量为 1ng/kg/min，持续 72 小时与安慰剂相比，在机械通气的 COVID-19 患者中的效果：一项随机对照试验研究方案的结构化总结。
Trials. 2020 Aug 26;21(1):746. doi: 10.1186/s13063-020-04696-2.
10
Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study.强化血小板抑制治疗可改善严重 COVID-19 合并高凝状态患者的低氧血症：一项病例对照、概念验证研究。
Pharmacol Res. 2020 Aug;158:104950. doi: 10.1016/j.phrs.2020.104950. Epub 2020 May 23.