University of Novi Sad, Faculty of Sciences, Department of Biology and Ecology, Trg Dositeja Obradovica 3, 21000 Novi Sad, Vojvodina, Serbia.
Quadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.
J Gen Virol. 2021 Jul;102(7). doi: 10.1099/jgv.0.001614.
Members of the family are non-enveloped flexible filamentous bacteriophages (600-2500×6-10 nm) with supercoiled, circular, positive-sense, single-stranded DNA genomes of 5.5-10.6 kb, encoding 7-15 proteins. They absorb to the pili of Gram-negative bacteria and replicate their DNA by a rolling-circle mechanism with progeny released from cells by extrusion without killing the host. Phage DNA can persist extra-chromosomally or integrate into the bacterial genome. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family , which is available at ictv.global/report/inoviridae.
科成员是无包膜的柔韧丝状噬菌体(600-2500×6-10nm),具有超螺旋、圆形、正链、单链 DNA 基因组,大小为 5.5-10.6kb,编码 7-15 种蛋白质。它们吸附在革兰氏阴性菌的菌毛上,并通过滚环机制复制其 DNA,子代通过挤压从细胞中释放出来,而不杀死宿主。噬菌体 DNA 可以在染色体外存在或整合到细菌基因组中。这是国际病毒分类委员会(ICTV)关于该科的报告摘要,可在 ictv.global/report/inoviridae 上查阅。