Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California, USA.
Ocular Imaging Research and Reading Center, Sunnyvale, California, USA.
Ocul Immunol Inflamm. 2022 Feb 17;30(2):276-281. doi: 10.1080/09273948.2021.1939391. Epub 2021 Jul 6.
A heatmap analysis of choroidal lesions in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) with or without uveitis was performed to determine if there were any distinguishing features among these uveitic entities.
Retrospective review of medical records was conducted at the Byers Eye Institute, Stanford. Fundus photographs were masked and placed on a standardized template. Lesions were identified and heatmaps were generated in a standardized fashion.
30 eyes were identified with PIC or MFC. Heatmap analysis revealed three distinct patterns of fundus lesions: posterior, peripheral, and combined. All patients with PIC had the posterior pattern. Patients with MFC had the peripheral or combined pattern, and all patients with MFC with uveitis had the combined pattern.
Three patterns of fundus lesions were identified in patients with PIC and MFC. PIC and MFC may represent two separate disease entities with distinct phenotypes of choroidal lesions.
对患有点状内层脉络膜病变（PIC）或多灶性脉络膜炎（MFC）伴或不伴葡萄膜炎的患者的脉络膜病变进行热图分析，以确定这些葡萄膜疾病实体之间是否存在任何区别特征。
对斯坦福大学拜尔斯眼科研究所的病历进行回顾性审查。眼底照片被屏蔽并放置在标准化模板上。识别病变并以标准化方式生成热图。
共确定了 30 只患有 PIC 或 MFC 的眼睛。热图分析显示出三种不同的眼底病变模式：后、周边和混合。所有患有 PIC 的患者均有后模式。患有 MFC 的患者有周边或混合模式，所有患有 MFC 伴葡萄膜炎的患者均有混合模式。
在患有 PIC 和 MFC 的患者中确定了三种眼底病变模式。PIC 和 MFC 可能代表两种不同的疾病实体，具有不同的脉络膜病变表型。
