Karetnikov Iu P, Vasil'eva I V
Probl Endokrinol (Mosk). 1987 Sep-Oct;33(5):23-7.
A comparative analysis of thyroid and calcium regulating functions in the diffuse toxic goiter was performed. At the initial stage TSH reaction to TRH was on a decrease in parallel with a sharp increase in the content of T4 T3. Two-third of the patients revealed an increase in the level of calcitonin resulting in an increase in the ratio of calcitropic hormones. In that case the content of ionized calcium was not increased. In one-third of the patients the level of calcitonin showed a tendency to a decrease in the normal ratio of calcitropic hormones not accompanied by change in the level of ionized calcium. In neurocirculatory dystonia polymorphism of clinical manifestation was accompanied by great variations (both rising and lowering tendencies) of all indices.
对弥漫性毒性甲状腺肿患者的甲状腺及钙调节功能进行了对比分析。在初始阶段，促甲状腺激素（TSH）对促甲状腺激素释放激素（TRH）的反应下降，同时甲状腺素（T4）和三碘甲状腺原氨酸（T3）含量急剧增加。三分之二的患者降钙素水平升高，导致钙调节激素比例增加。在此情况下，离子钙含量并未增加。三分之一的患者降钙素水平呈下降趋势，钙调节激素比例正常，且离子钙水平无变化。在神经循环性肌张力障碍中，临床表现的多态性伴随着所有指标的巨大变化（既有升高趋势也有降低趋势）。
