Department of Psychology, Graduate School of Dankook University.
Department of Psychology and Psychotherapy, College of Health Science.
Medicine (Baltimore). 2021 Jul 9;100(27):e26442. doi: 10.1097/MD.0000000000026442.
Chronic diarrhea and constipation are common in adolescents and are associated with depression and anxiety. However, the association was not reported in adolescents adjusted for other psychological factors (resilience, personality traits, perceived stress, and suicidal ideation). Therefore, we investigated the significant psychological factors predicting chronic diarrhea and constipation in adjusted individuals for co-variables.A total of 819 Korean high school students who completed bowel health and psychological questionnaires were enrolled in this study. Depression and anxiety were assessed using validated questionnaires. We used multivariate analyses, controlling for demographic, dietary, lifestyle, and psychological variables to predict chronic diarrhea and constipation.Chronic diarrhea and constipation were more common in individuals with depression (22.3% and 18.6%, respectively) than in individuals with no depression (7.0% and 10.9%, respectively). In addition, they were more prevalent in individuals with anxiety (24.5% and 18.6%, respectively) than in individuals with no anxiety (9.1% and 12.7%, respectively). Multivariate analyses showed that resilience (adjusted risk ratio [aRR] = 0.98, adjusted 95% confidence interval [CI] = 0.97-0.99), moderate (aRR = 6.77, adjusted 95% CI = 3.55-12.91), and severe depression (aRR = 7.42, adjusted 95% CI = 3.61-15.27) were associated with chronic diarrhea. Only mild depression was associated with chronic constipation (aRR = 2.14, adjusted 95% CI = 1.36-3.38). However, anxiety was not significantly associated with chronic diarrhea or constipation.Among the psychological factors predicting disordered bowel habits, resilience and moderate and severe depression were significant predictors of chronic diarrhea, but not anxiety. Furthermore, only mild depression was an independent predictor of chronic constipation.
慢性腹泻和便秘在青少年中很常见，并且与抑郁和焦虑有关。然而，在调整了其他心理因素（韧性、人格特质、感知压力和自杀意念）后，青少年中并未报告这种关联。因此，我们研究了调整了协变量后，预测慢性腹泻和便秘的显著心理因素。
本研究共纳入了 819 名完成了肠道健康和心理问卷的韩国高中生。使用经过验证的问卷评估抑郁和焦虑。我们使用多元分析，控制了人口统计学、饮食、生活方式和心理变量，以预测慢性腹泻和便秘。
慢性腹泻和便秘在抑郁患者中更为常见（分别为 22.3%和 18.6%），而在无抑郁患者中分别为 7.0%和 10.9%。此外，在焦虑患者中更为常见（分别为 24.5%和 18.6%），而在无焦虑患者中分别为 9.1%和 12.7%。多元分析显示，韧性（调整后的风险比[aRR] = 0.98，调整后的 95%置信区间[CI] = 0.97-0.99）、中度（aRR = 6.77，调整后的 95% CI = 3.55-12.91）和重度抑郁（aRR = 7.42，调整后的 95% CI = 3.61-15.27）与慢性腹泻相关。只有轻度抑郁与慢性便秘相关（aRR = 2.14，调整后的 95% CI = 1.36-3.38）。然而，焦虑与慢性腹泻或便秘无显著相关性。
在预测肠道紊乱的心理因素中，韧性和中重度抑郁是慢性腹泻的显著预测因素，但焦虑不是。此外，只有轻度抑郁是慢性便秘的独立预测因素。
