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农村和城市向欧洲的移民与心血管疾病风险的关系:你从哪里移民过来有关系吗?

Rural and urban migration to Europe in relation to cardiovascular disease risk: does it matter where you migrate from?

机构信息

Department of Public Health, Amsterdam Public Health Research Institute, Academic Medical Center, Amsterdam UMC, University of Amsterdam, Meibergdreef 15, 1105AZ, Amsterdam, the Netherlands.

Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3508GA, Utrecht, the Netherlands; School of Public Health, Kwame Nkrumah University of Science and Technology, Accra Rd, Kumasi, Ghana.

出版信息

Public Health. 2021 Jul;196:172-178. doi: 10.1016/j.puhe.2021.06.001. Epub 2021 Jul 4.

Abstract

OBJECTIVES

To assess whether the environmental context (i.e. rural vs urban) in which individuals in low- and middle-income countries have resided most of their lives is associated with estimated cardiovascular disease (CVD) risk after migration to a high-income country.

STUDY DESIGN

Data from the Research on Obesity and Diabetes among African Migrants (RODAM) study were used including 1699 Ghanaian participants aged 40-79 years who had migrated to Europe from Ghana (1549 of urban origin, 150 of rural origin).

METHODS

Ten-year CVD risk was estimated using the Pooled Cohort Equation, with estimates ≥7.5% defining elevated CVD risk. Comparisons between urban and rural origin migrant groups were made using proportions and adjusted odds ratios (ORs).

RESULTS

The proportion of migrants with an elevated CVD-risk score was substantially higher among rural migrants than among urban migrants (45% vs. 37%, OR = 1.44, 95% confidence interval [CI]:1.03-2.02), which persisted after adjustment for education level, site of residence in Europe (London, Amsterdam or Berlin), length of stay in Europe, physical activity, energy intake and alcohol consumption (OR = 1.67, 95% CI: 1.05-2.67).

CONCLUSION

Our findings indicate that migrants who spent most of their lives in a rural setting before migration to Europe may have a higher CVD risk than those of urban origins. Further work is needed to confirm these findings in other migrant populations and to unravel the mechanisms driving the differential CVD risk between urban and rural migrants.

摘要

目的

评估个体在中低收入国家生活的环境背景(即农村与城市)是否与移民到高收入国家后的心血管疾病(CVD)风险估计有关。

研究设计

本研究使用了非洲移民肥胖和糖尿病研究(RODAM)的数据,共纳入 1699 名年龄在 40-79 岁的加纳移民,他们从加纳移民到欧洲(1549 名来自城市,150 名来自农村)。

方法

采用聚合队列方程估计 10 年 CVD 风险,估计值≥7.5%定义为 CVD 风险升高。使用比例和调整后的比值比(OR)比较城乡移民群体之间的差异。

结果

农村移民中 CVD 风险评分升高的比例明显高于城市移民(45%比 37%,OR=1.44,95%置信区间[CI]:1.03-2.02),这种差异在调整教育水平、欧洲居住地(伦敦、阿姆斯特丹或柏林)、在欧洲的居住时间、体力活动、能量摄入和酒精消耗后仍然存在(OR=1.67,95%CI:1.05-2.67)。

结论

我们的研究结果表明,在移民到欧洲之前,一生中大部分时间生活在农村环境中的移民可能比来自城市的移民有更高的 CVD 风险。需要进一步的研究来在其他移民群体中证实这些发现,并揭示城乡移民之间 CVD 风险差异的驱动机制。

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