Tuk B, Corrales D
Servicio de Anatomía Patológica, Hospital México.
Rev Biol Trop. 1986 Nov;34(2):167-70.
In recent years scanning electron microscopy has been used in gastric biopsy studies, contributing to better recognition of intestinal metaplasia and carcinoma, as a complement to light and transmission electron microscopy. During the second half of 1983, 53 cases of gastric carcinoma were diagnosed at the Department of Pathology of Hospital Mexico, of which six were studied ultrastructurally. A pattern similar to that of intestinal epithelium was found in cases of intestinal metaplasia. Well differentiated adenocarcinomas showed marked tumor cell proliferation with irregular "projections". In poorly differentiated carcinomas, changes were limited to areas where tumor cells invaded the epithelial surface. In summary, scanning electron microscopy is of great help in research and diagnosis of pathologic changes occurring in mucosal surfaces.
近年来，扫描电子显微镜已用于胃活检研究，作为光学显微镜和透射电子显微镜的补充，有助于更好地识别肠化生和癌。1983年下半年，墨西哥医院病理科诊断出53例胃癌，其中6例进行了超微结构研究。在肠化生病例中发现了与肠上皮相似的模式。高分化腺癌显示出明显的肿瘤细胞增殖，伴有不规则的“突起”。在低分化癌中，变化仅限于肿瘤细胞侵犯上皮表面的区域。总之，扫描电子显微镜对研究和诊断黏膜表面发生的病理变化有很大帮助。
