Oka Anak Agung Gde, Duarsa Gede Wirya Kusuma, Novianti Putu Astri, Mahadewa Tjokorda Gde Bagus, Ryalino Christopher
Departments of Urology, Faculty of Medicine, Udayana University, Denpasar, Indonesia.
Surgery, Faculty of Medicine, Udayana University, Denpasar, Indonesia.
Res Rep Urol. 2019 Apr 10;11:91-96. doi: 10.2147/RRU.S189414. eCollection 2019.
Erectile dysfunction (ED) after a prostate-transurethral resection (P-TUR) is one of the problems in the treatment of benign prostatic hyperplasia (BPH) that may affect the quality of life in middle-aged and older men. The aim of this study was to investigate the impact of P-TUR on ED in BPH patients. This study was conducted on 83 patients suffering from BPH that underwent a P-TUR. Clinically, testosterone levels, prostatic-specific antigen (PSA) levels, and prostate volume were measured before the P-TUR. Erectile function was measured prior to the P-TUR, as well as at 1 and 3 months after the P-TUR using the International Index of Erectile Function (IIEF). Suitability test of the model was done in a structural equation. Data were analyzed using the chi-square ( ) test by Analysis of Moment Structure (AMOS) software version 21. The effects of PSA to IIEF before, 1 month after, and 3 months after P-TUR were 0.116, 0.084, and 0.097, respectively. The effects of body mass index to IIEF before, 1 month after, and 3 months after P-TUR were 0.180, 0.066, and 0.164, respectively. The effects of prostate volume to IIEF before, 1 month after, and 3 months after P-TUR were 0.049, 0.004, and 0.011, respectively. The effects of testosterone to IIEF before, 1 month after, and 3 months after P-TUR were -0.029, -0.453, and -0.415, respectively. The effects of age to IIEF before, 1 month after, and 3 months after P-TUR were -0.444, 0.921, and 0.911, respectively. There was a significant improvement of erectile function in patients that underwent P-TUR who previously had preoperative ED, especially 3 months after the surgery.
经尿道前列腺切除术(P-TUR)后勃起功能障碍(ED)是良性前列腺增生(BPH)治疗中的问题之一,可能会影响中老年男性的生活质量。本研究的目的是调查经尿道前列腺切除术对良性前列腺增生患者勃起功能障碍的影响。本研究对83例接受经尿道前列腺切除术的良性前列腺增生患者进行。临床上,在经尿道前列腺切除术之前测量睾酮水平、前列腺特异性抗原(PSA)水平和前列腺体积。在经尿道前列腺切除术之前以及术后1个月和3个月使用国际勃起功能指数(IIEF)测量勃起功能。在结构方程中对模型进行适配性检验。数据采用Mplus软件版本8.3进行分析。经尿道前列腺切除术之前、术后1个月和3个月时,PSA对IIEF的影响分别为0.116、0.084和0.097。经尿道前列腺切除术之前、术后1个月和3个月时,体重指数对IIEF的影响分别为0.180、0.066和0.164。经尿道前列腺切除术之前、术后1个月和3个月时,前列腺体积对IIEF的影响分别为0.049、0.004和0.011。经尿道前列腺切除术之前、术后1个月和3个月时,睾酮对IIEF的影响分别为-0.029、-0.453和-0.415。经尿道前列腺切除术之前、术后1个月和3个月时,年龄对IIEF的影响分别为-0.444、0.921和0.911。之前存在术前勃起功能障碍且接受经尿道前列腺切除术的患者,其勃起功能有显著改善,尤其是在术后3个月。