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一种难以愈合的咬伤:诱发失代偿期肝硬化。

A bite difficult to heal: induced decompensated hepatic cirrhosis.

作者信息

Patel Hiren, Patel Nirali, Patel Harsh, Chow Robert Dobbin

机构信息

Department of Medicine, American University of Antigua College of Medicine, Coolidge, Antigua.

University of Maryland Medical Center Midtown Campus, University of Maryland School of Medicine, Baltimore, MD, USA.

出版信息

J Community Hosp Intern Med Perspect. 2021 May 10;11(3):379-383. doi: 10.1080/20009666.2021.1906490. eCollection 2021.

Abstract

is a gram-negative bacterium that colonizes domestic animals. It is commonly implicated in bite and scratch wounds, potentially resulting in cellulitis, superficial abscesses, osteomyelitis, or peritonitis. Rarely, it can lead to bacteremia and septic shock in high-risk patients. We present an atypical presentation of bacteremia and sepsis in a patient with stage 4 decompensated cirrhosis. The patient presented with melena and altered mental status with CT imaging showing a heterogeneous nodular liver along with an enlarged portal vein, gastric varices, and ascites consistent with decompensated cirrhosis. The patient was initially managed with intravenous (IV) octreotide and pantoprazole, blood and platelet transfusions, and broad-spectrum antibiotics. Upper endoscopy showed diffuse non-bleeding esophageal and gastric varices, which required band ligation and continued IV octreotide therapy. The infection resolved after a 7-day course of IV ceftriaxone.

摘要

是一种定植于家畜的革兰氏阴性菌。它通常与咬伤和抓伤伤口有关,可能导致蜂窝织炎、浅表脓肿、骨髓炎或腹膜炎。在高危患者中,它很少会导致菌血症和感染性休克。我们报告了一名失代偿期肝硬化4期患者菌血症和脓毒症的非典型表现。该患者出现黑便和精神状态改变,CT成像显示肝脏呈不均匀结节状,同时门静脉增宽、胃静脉曲张和腹水,符合失代偿期肝硬化表现。患者最初接受静脉注射奥曲肽和泮托拉唑、输血和血小板以及广谱抗生素治疗。上消化道内镜检查显示弥漫性无出血性食管和胃静脉曲张,需要进行套扎术并持续静脉注射奥曲肽治疗。静脉注射头孢曲松7天疗程后感染得到解决。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/267d/8118415/fb0f8b001561/ZJCH_A_1906490_F0001_OC.jpg

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