假设：挥发性麻醉剂会增强母体与胎儿之间的经胎盘交换。一项关于与恩氟烷麻醉相关的胎儿头皮血气变化的初步研究。
Hypothesis: volatile anaesthetic agents enhance transplacental exchange between mother and fetus. A preliminary study of fetal scalp blood gas changes associated with enflurane anaesthesia.
作者信息
Downing J W, Fairbrother P E, Buley R J, Brock-Utne J G, Kambaran S R, Macpherson T A
出版信息
S Afr Med J. 1979 Jan 6;55(1):17-20.
PMID:34236
Abstract
A hypothesis that volatile anaesthetic agents, represented by enflurane, facilitate transplacental exchange was tested by simultaneous blood sampling of both mother and fetus. A trend towards improved fetal scalp blood gas status and maternal-to-fetal acid-base matching was observed with enflurane. Our results encourage further research into the feasibility of intra-uterine fetal resuscitation by anaesthetically induced promotion of intervillous perfusion.
摘要
以安氟醚为代表的挥发性麻醉剂可促进经胎盘交换这一假说，通过同时采集母体和胎儿的血液样本进行了验证。使用安氟醚时，观察到胎儿头皮血气状态改善以及母胎酸碱匹配度提高的趋势。我们的研究结果鼓励进一步探讨通过麻醉诱导促进绒毛间隙灌注进行宫内胎儿复苏的可行性。
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