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基于糖尿病预防计划的生活方式干预对心血管健康指标的影响。

The Impact of a Yearlong Diabetes Prevention Program-Based Lifestyle Intervention on Cardiovascular Health Metrics.

机构信息

University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.

University of Utah School of Medicine, Salt Lake City, UT, USA.

出版信息

J Prim Care Community Health. 2021 Jan-Dec;12:21501327211029816. doi: 10.1177/21501327211029816.

DOI:10.1177/21501327211029816
PMID:34236004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8274083/
Abstract

INTRODUCTION

The American Heart Association created "Life's Simple Seven" metrics to estimate progress toward improving US cardiovascular health in a standardized manner. Given the widespread use of federally funded Diabetes Prevention Program (DPP)-based lifestyle interventions such as the Group Lifestyle Balance (DPP-GLB), evaluation of change in health metrics within such a program is of national interest. This study examined change in cardiovascular health metric scores during the course of a yearlong DPP-GLB intervention.

METHODS

Data were combined from 2 similar randomized trials offering a community based DPP-GLB lifestyle intervention to overweight/obese individuals with prediabetes and/or metabolic syndrome. Pre/post lifestyle intervention participation changes in 5 of the 7 cardiovascular health metrics were examined at 6 and 12 months (BMI, blood pressure, total cholesterol, fasting plasma glucose, physical activity). Smoking was rare and diet was not measured.

RESULTS

Among 305 participants with complete data (81.8% of 373 eligible adults), significant improvements were demonstrated in all 5 risk factors measured continuously at 6 and 12 months. There were significant positive shifts in the "ideal" and "total" metric scores at both time points. Also noted were beneficial shifts in the proportion of participants across categories for BMI, activity, and blood pressure.

CONCLUSION

AHA-metrics could have clinical utility in estimating an individual's cardiovascular health status and in capturing improvement in cardiometabolic/behavioral risk factors resulting from participation in a community-based translation of the DPP lifestyle intervention.

摘要

简介

美国心脏协会创建了“生命的七大简单指标”,以标准化的方式评估美国心血管健康改善的进展。鉴于广泛使用联邦资助的基于糖尿病预防计划(DPP)的生活方式干预措施,如团体生活方式平衡(DPP-GLB),评估此类计划中健康指标的变化具有国家利益。本研究检查了为期一年的 DPP-GLB 干预过程中心血管健康指标得分的变化。

方法

数据来自两项类似的随机试验,为超重/肥胖的糖尿病前期和/或代谢综合征患者提供基于社区的 DPP-GLB 生活方式干预。在 6 个月和 12 个月时(BMI、血压、总胆固醇、空腹血糖、体力活动),检查了 7 项心血管健康指标中的 5 项在生活方式干预前后的变化。吸烟很少,饮食未测量。

结果

在 305 名具有完整数据的参与者中(373 名合格成年人中有 81.8%),所有 5 项连续测量的风险因素在 6 个月和 12 个月时均显示出显著改善。在两个时间点,“理想”和“总”指标得分都有显著的积极变化。还注意到 BMI、活动和血压的参与者比例在各分类中均有有益的变化。

结论

AHA 指标可用于估计个体的心血管健康状况,并可捕捉到参与基于社区的 DPP 生活方式干预所导致的心血管代谢/行为风险因素的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9efb/8274083/180ab0b0d141/10.1177_21501327211029816-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9efb/8274083/180ab0b0d141/10.1177_21501327211029816-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9efb/8274083/180ab0b0d141/10.1177_21501327211029816-fig1.jpg

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