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[牙周炎——一种常见疾病的治疗]

[Periodontitis-therapy of a widespread disease].

作者信息

Dannewitz Bettina, Holtfreter Birte, Eickholz Peter

机构信息

Poliklinik für Parodontologie, Zentrum der Zahn‑, Mund- und Kieferheilkunde, Johann Wolfgang Goethe-Universität Frankfurt am Main, Theodor-Stern-Kai 7, 60596, Frankfurt am Main, Deutschland.

Zahnärztliche Gemeinschaftspraxis Dres. Dannewitz & Glass, Weilburg, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021 Aug;64(8):931-940. doi: 10.1007/s00103-021-03373-2. Epub 2021 Jul 8.

DOI:10.1007/s00103-021-03373-2
PMID:34236451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8264996/
Abstract

Periodontitis is a chronic inflammatory noncommunicable disease that affects all parts of the periodontium and causes irreversible damage. It is estimated that around 10 million people in Germany suffer from severe forms of periodontitis. The disease usually shows few or only mild symptoms over many years, which are often not perceived or correctly classified by the patient. A lack of awareness could lead to dental treatment being sought in an advanced stage of the disease when extensive therapeutic measures have become necessary and the prognosis for tooth retention has worsened. The periodontal screening index (PSI) is a simple and rapid tool that is used to assess the level of further examination needed. The index is now carried out on many patients. However, the number of treatments remain low and behind what is necessary to reduce the existing burden of periodontitis. Every dental practice must be able to implement periodontal therapy in their clinical setting. Periodontal specialists can support general dentists significantly, especially in the treatment of severe forms of periodontitis. This requires an upgrading of the subject in university education, but also an increasing postgraduate differentiation of specialized dentists for periodontology. The new treatment guidelines for PAR (periodontal) therapy allow periodontal treatment on the basis of internationally recognized scientific standards and thus improve the framework conditions for therapy in the dental practice.

摘要

牙周炎是一种慢性炎症性非传染性疾病,会影响牙周组织的各个部分并造成不可逆的损害。据估计,德国约有1000万人患有严重形式的牙周炎。多年来,这种疾病通常表现出很少或只有轻微症状,患者往往没有察觉到或正确分类这些症状。缺乏认识可能导致在疾病晚期才寻求牙科治疗,此时需要采取广泛的治疗措施,牙齿保留的预后也会变差。牙周筛查指数(PSI)是一种简单快速的工具,用于评估所需的进一步检查水平。现在许多患者都进行了该指数检查。然而,治疗的数量仍然很低,低于减轻现有牙周炎负担所需的数量。每个牙科诊所都必须能够在其临床环境中实施牙周治疗。牙周专科医生可以为普通牙医提供大力支持,尤其是在治疗严重形式的牙周炎方面。这需要在大学教育中提升该学科的地位,同时也需要增加牙周病专科牙医的研究生分化。新的PAR(牙周)治疗指南允许在国际认可的科学标准基础上进行牙周治疗,从而改善牙科诊所治疗的框架条件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/8819f5d716ee/103_2021_3373_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/e714c108daf7/103_2021_3373_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/318905095f41/103_2021_3373_Fig3_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/8819f5d716ee/103_2021_3373_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/e714c108daf7/103_2021_3373_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/a377b1f42651/103_2021_3373_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/318905095f41/103_2021_3373_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/65529128e952/103_2021_3373_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3782/8316230/8819f5d716ee/103_2021_3373_Fig5_HTML.jpg

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本文引用的文献

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Association between periodontitis and severity of COVID-19 infection: A case-control study.牙周炎与 COVID-19 感染严重程度的关系:一项病例对照研究。
J Clin Periodontol. 2021 Apr;48(4):483-491. doi: 10.1111/jcpe.13435. Epub 2021 Feb 15.
2
Periodontal disease and quality of life: Umbrella review of systematic reviews.牙周病与生活质量:系统评价的伞式综述。
J Periodontal Res. 2021 Jan;56(1):1-17. doi: 10.1111/jre.12805. Epub 2020 Sep 23.
3
Treatment of stage I-III periodontitis-The EFP S3 level clinical practice guideline.
评估一种配备基于人工智能应用程序的口腔内摄像头用于牙龈炎检测的情况。
J Clin Med. 2025 Aug 7;14(15):5580. doi: 10.3390/jcm14155580.
4
Professional biofilm management during supportive periodontal therapy-a longitudinal observational study.支持性牙周治疗期间的专业生物膜管理——一项纵向观察性研究
BMC Oral Health. 2025 Jul 30;25(1):1277. doi: 10.1186/s12903-025-06642-7.
5
Mechanism of Salvia miltiorrhiza in the treatment of periodontitis: integrative analyses via network pharmacology, molecular dynamics, and cellular assays.丹参治疗牙周炎的机制:通过网络药理学、分子动力学和细胞试验的综合分析
BMC Complement Med Ther. 2025 Jul 28;25(1):291. doi: 10.1186/s12906-025-05040-4.
6
Identification and validation of endoplasmic reticulum autophagy-related potential biomarkers in periodontitis.牙周炎中内质网自噬相关潜在生物标志物的鉴定与验证
Sci Rep. 2025 Jul 6;15(1):24151. doi: 10.1038/s41598-025-08180-2.
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-dependent deacetylation in macrophages inhibits periodontitis.巨噬细胞中依赖于……的去乙酰化作用可抑制牙周炎。 (注:原文“-dependent”前内容缺失)
Front Pharmacol. 2025 Jun 18;16:1574141. doi: 10.3389/fphar.2025.1574141. eCollection 2025.
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Advances of 3D bioprinting technology for periodontal tissue regeneration.用于牙周组织再生的3D生物打印技术进展
iScience. 2025 Apr 25;28(6):112532. doi: 10.1016/j.isci.2025.112532. eCollection 2025 Jun 20.
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MicroRNAs modulation by isodrimeninol from in periodontitis-associated cellular models: preliminary results.异去甲蟛蜞菊内酯在牙周炎相关细胞模型中对微小RNA的调控:初步结果
Front Oral Health. 2025 May 21;6:1489823. doi: 10.3389/froh.2025.1489823. eCollection 2025.
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Therapeutic potential of boric acid as a local drug delivery agent in periodontitis: a comprehensive systematic review and meta-analysis.硼酸作为牙周炎局部给药载体的治疗潜力:一项全面的系统评价和荟萃分析
BMC Oral Health. 2025 Jan 17;25(1):88. doi: 10.1186/s12903-025-05445-0.
牙周炎 I-III 期的治疗——EFP S3 级临床实践指南。
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J Periodontol. 2019 Apr;90(4):323-330. doi: 10.1002/JPER.18-0417. Epub 2018 Nov 20.
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Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.牙周炎的分期和分级:新分类和病例定义的框架和建议。
J Clin Periodontol. 2018 Jun;45 Suppl 20:S149-S161. doi: 10.1111/jcpe.12945.