Kaarela K, Lehtinen K, Luukkainen R
Rheumatism Foundation Hospital, Heinola, Finland.
Scand J Rheumatol. 1987;16(6):403-6. doi: 10.3109/03009748709165410.
In a prospective study of recent arthritis, 103 patients had rheumatoid arthritis (RA), 63 seronegative oligoarthritis (SO), 67 reactive arthritis (REA), 20 ankylosing spondylitis (AS), and 13 psoriatic arthritis (PA). At the 8-year check-up, 36% of patients with RA were at work, compared with 69% in PA (p less than 0.002), and 85-90% in AS, SO, and REA (p less than 0.001). Correspondingly 43% of the RA patients were disabled by arthritis, compared with 23% in PA (NS), 15% in AS (p less than 0.005), none in SO, and 4% in REA (p less than 0.001). No significant differences in work capacity were noted between patients with PA, AS, SO or REA. In RA, the educational backgrounds of patients unable to work (44 patients) and able to work (37 patients) did not differ from each other or from the overall population of Finland, but a significantly (p less than 0.01) smaller number of patients with arduous work were able to continue at work. The mean age of 49 years for RA patients unable to work differed highly significantly (p less than 0.001) from the 35 years of RA patients at work. However, the weightiest cause of limited work capacity was severity of disease.
在一项针对近期关节炎患者的前瞻性研究中,103例患者患有类风湿性关节炎(RA),63例患有血清阴性寡关节炎(SO),67例患有反应性关节炎(REA),20例患有强直性脊柱炎(AS),13例患有银屑病关节炎(PA)。在8年的随访检查中,36%的RA患者仍在工作,而PA患者的这一比例为69%(p<0.002),AS、SO和REA患者的比例为85%-90%(p<0.001)。相应地,43%的RA患者因关节炎而致残,PA患者的这一比例为23%(无显著差异),AS患者为15%(p<0.005),SO患者无一例致残,REA患者为4%(p<0.001)。PA、AS、SO或REA患者之间的工作能力没有显著差异。在RA患者中,无法工作的患者(44例)和能够工作的患者(37例)的教育背景与芬兰总体人群没有差异,但从事艰苦工作的患者中能够继续工作的人数明显较少(p<0.01)。无法工作的RA患者平均年龄为49岁,与仍在工作的RA患者的35岁有极显著差异(p<0.001)。然而,工作能力受限的最主要原因是疾病的严重程度。