希腊北部艾滋病毒血清阳性患者对抗逆转录病毒疗法的依从性。主要影响因素。
Adherence to antiretroviral therapy among HIV seropositive patients in northern Greece. Major factors of influence.
作者信息
Goma F, Papazisis G, Karakiulakis G
机构信息
National Public Health Organization, School of Medicine, Aristotle University of Thessaloniki Greece.
Department of Pharmacology, School of Medicine, Aristotle University of Thessaloniki Greece.
出版信息
Hippokratia. 2020 Jul-Sep;24(3):114-119.
BACKGROUND
Adherence to HIV antiretroviral therapy (ART) is of great importance for reducing viral load and the eventual treatment of the patients and minimizing infectivity. This study aimed to investigate adherence to ART among people living with HIV in northern Greece and investigate the factors influencing adherence to ART.
METHODS
A correlational study was performed on a cohort of 112 seropositive individuals (100 men and 12 women) with a mean age of 37.14 years. The simplified medication adherence questionnaire (SMAQ) was used to assess adherence. In addition, the perceived available support questionnaire (PAS) for social support assessment was utilized to evaluate the perceived social support.
RESULTS
Approximately 60% of patients were found to be nonadherent to ART. Important factors affecting adherence are educational level, social support, and use of substances.
CONCLUSIONS
The results show that a significant proportion of the cohort of patients investigated from northern Greece does not show adherence to ART. Several factors were identified to be of significant influence, which should be taken into consideration by the Greek healthcare providers. HIPPOKRATIA 2020, 24(3): 114-119.
背景
坚持接受HIV抗逆转录病毒疗法（ART）对于降低病毒载量、最终治疗患者以及将传染性降至最低至关重要。本研究旨在调查希腊北部HIV感染者对ART的依从性，并探究影响ART依从性的因素。
方法
对112名血清学阳性个体（100名男性和12名女性）组成的队列进行了相关性研究，这些个体的平均年龄为37.14岁。采用简化药物依从性问卷（SMAQ）评估依从性。此外，使用感知可用支持问卷（PAS）进行社会支持评估，以评价感知到的社会支持。
结果
发现约60%的患者未坚持接受ART。影响依从性的重要因素包括教育水平、社会支持和物质使用情况。
结论
结果表明，来自希腊北部的被调查患者队列中有很大一部分未坚持接受ART。已确定有几个因素具有重大影响，希腊医疗服务提供者应予以考虑。《希波克拉底》2020年，第24卷（3）：114 - 119页。
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