Chen Shih-Hao, Chen Wen-Jer, Wu Meng-Huang, Liao Jen-Chung, Fu Chen-Ju
Department of Orthopaedic Surgery, Buddhist Tzu-Chi General Hospital at Taichung and Tzu-Chi University, Hualien City.
Department of Orthopaedic Surgery, Chang-Gung Memorial Hospital at Linkou and Chang-Gung University, Taoyuan.
Clin Spine Surg. 2018 Jul;31(6):225-238. doi: 10.1097/BSD.0000000000000633.
Surgical site infections after posterior spinal surgery may lead to spondylodiscitis, pseudarthrosis, correction loss, adverse neurological sequelae, sepsis, and poor outcomes if not treated immediately. Infection rates vary depending on the type and extent of operative procedures, use of instrumentation, and patients' risk factors. Image evaluation is crucial for early diagnosis and should be complementary to clinical routes, laboratory survey, and treatment timing. Magnetic resonance imaging detects early inflammatory infiltration into the vertebrae and soft tissues, including hyperemic changes of edematous marrow, vertebral endplate, and abscess or phlegmon accumulation around the intervertebral disk, epidural, and paravertebral spaces. Aggressive surgical treatment can eradicate infection sources, obtain a stable wound closure, decrease morbidity, and restore spinal integrity. Organ/space infection is defined as any body parts opened to manipulate other than superficial/deep incision. Advanced magnetic resonance imaging evaluating abnormal fluid accumulation, heterogenous contrast enhancement of the endplate erosion due to cage/screw infection is categorized to inform a presumptive diagnosis for early implant salvage. However, patients' defense response, infection severity, bacteriology, treatment timing, spinal stability, and available medical and surgical options must be fully considered. Revision surgery is indicated for pseudarthrosis, implant loosening with correction loss, recalcitrant spondylodiscitis, and adjacent segment diseases for infection control.
后路脊柱手术后的手术部位感染若不立即治疗,可能会导致脊椎椎间盘炎、假关节形成、矫正丢失、不良神经后遗症、败血症及预后不良。感染率因手术操作的类型和范围、器械的使用以及患者的风险因素而异。影像评估对于早期诊断至关重要,且应与临床路径、实验室检查及治疗时机相辅相成。磁共振成像可检测到早期炎症浸润至椎体和软组织,包括骨髓水肿、椎体终板的充血变化以及椎间盘周围、硬膜外和椎旁间隙的脓肿或蜂窝织炎积聚。积极的手术治疗可根除感染源,实现伤口稳定闭合,降低发病率并恢复脊柱完整性。器官/腔隙感染定义为除浅部/深部切口外任何为进行操作而打开的身体部位。评估因椎间融合器/螺钉感染导致的终板侵蚀伴异常液体积聚、不均匀对比增强的先进磁共振成像被归类用于为早期植入物挽救提供初步诊断。然而,必须充分考虑患者的防御反应、感染严重程度、细菌学、治疗时机、脊柱稳定性以及可用的医疗和手术选择。翻修手术适用于假关节形成、伴有矫正丢失的植入物松动、难治性脊椎椎间盘炎以及用于控制感染的相邻节段疾病。