保肢性半骨盆切除术治疗尤因肉瘤后成功妊娠：病例报告及文献复习。
Successful pregnancy after limb-sparing hemipelvectomy for Ewing sarcoma: Case report and literature review.
机构信息
Department of Obstetrics and Gynecology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan; Department of Obstetrics and Gynecology, St. Marianna University School of Medicine, Kanagawa, Japan.
Department of Obstetrics and Gynecology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.
出版信息
Taiwan J Obstet Gynecol. 2021 Jul;60(4):787-790. doi: 10.1016/j.tjog.2021.05.038.
OBJECTIVE
We present a case of successful pregnancy in a patient who underwent limb-sparing hemipelvectomy combined with multi-agent chemotherapy and radiotherapy for Ewing sarcoma.
CASE REPORT
A 17-year-old girl was diagnosed with Ewing sarcoma of the left pelvis at the age of 17 and received limb-sparing hemipelvectomy combined with multi-agent chemotherapy and radiotherapy. The patient received oral contraceptives as hormone replacement therapy after completion of treatment. A normal menstruation cycle restored after the withdrawal of oral contraceptives. The patient spontaneously conceived at the age of 25. The patient complained of difficulty walking due to pelvic distortion during pregnancy and delivered a healthy neonate at term by cesarean section.
CONCLUSION
Successful pregnancy and delivery can be achieved after limb-sparing hemipelvectomy combined with chemotherapy and radiotherapy for Ewing sarcoma. Our report provides important information on perinatal management, given the low incidence of pregnancy following treatment of Ewing sarcoma in the pelvis.
目的
我们报告了一例成功妊娠的病例，患者为 17 岁女性，因尤文肉瘤接受了保肢半骨盆切除术联合多药化疗和放疗。
病例报告
患者 17 岁时被诊断为左骨盆尤文肉瘤，并接受了保肢半骨盆切除术联合多药化疗和放疗。治疗完成后，患者接受口服避孕药作为激素替代疗法。停用避孕药后，月经周期恢复正常。患者 25 岁时自然受孕。患者在妊娠期间因骨盆变形出现行走困难，并通过剖宫产足月分娩了一名健康新生儿。
结论
尤文肉瘤行保肢半骨盆切除术联合化疗和放疗后可成功妊娠和分娩。鉴于骨盆尤文肉瘤治疗后妊娠发生率较低，我们的报告为围产期管理提供了重要信息。
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