在一些大肠杆菌K-12实验室菌株中发现的赋予对氯化汞和氯化钴更高敏感性的质粒。
Plasmid conferring increased sensitivity to mercuric chloride and cobalt chloride found in some laboratory strains of Escherichia coli K-12.
作者信息
Wang P Y, Relf J, Palchaudhuri S, Iyer V N
出版信息
J Bacteriol. 1978 Feb;133(2):1042-3. doi: 10.1128/jb.133.2.1042-1043.1978.
Abstract
Some lines of the widely used strain CR34 of Escherichia coli K-12 carry a plasmid. The plasmid has a mass of 12 +/- 2 X 10(6) megadaltons and is maintained at a low copy number per cell (1 to 2), and this number is not amplified by growth of cells in the presence of chloramphenicol. The plasmid is designated as pCU3. The presence of pCU3 confers on the strain increased sensitivity to mercuric chloride and cobalt chloride. The plasmid has also been observed to fuse or recombine with the plasmid R64-11.
摘要
广泛使用的大肠杆菌K-12菌株CR34的某些品系携带一种质粒。该质粒的质量为12 +/- 2×10(6)兆道尔顿，在每个细胞中以低拷贝数（1至2个）维持，并且这个数量不会因细胞在氯霉素存在下生长而扩增。该质粒被命名为pCU3。pCU3的存在使该菌株对氯化汞和氯化钴的敏感性增加。还观察到该质粒与质粒R64-11融合或重组。
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