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2
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Pheochromocytoma and Paraganglioma: From Epidemiology to Clinical Findings.嗜铬细胞瘤和副神经节瘤:从流行病学到临床发现
Sisli Etfal Hastan Tip Bul. 2020 Jun 3;54(2):159-168. doi: 10.14744/SEMB.2020.18794. eCollection 2020.
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Current Management of Pheochromocytoma/Paraganglioma: A Guide for the Practicing Clinician in the Era of Precision Medicine.嗜铬细胞瘤/副神经节瘤的当前管理:精准医学时代执业临床医生指南
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Performance of Ga-DOTA-Conjugated Somatostatin Receptor-Targeting Peptide PET in Detection of Pheochromocytoma and Paraganglioma: A Systematic Review and Metaanalysis.镓-DOTA 偶联生长抑素受体靶向肽 PET 在嗜铬细胞瘤和副神经节瘤检测中的性能:系统评价和荟萃分析。
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Metabologenomics of Phaeochromocytoma and Paraganglioma: An Integrated Approach for Personalised Biochemical and Genetic Testing.嗜铬细胞瘤和副神经节瘤的代谢基因组学:个性化生化和基因检测的综合方法。
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Staging and functional characterization of pheochromocytoma and paraganglioma by 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography.18F-氟脱氧葡萄糖(18F-FDG)正电子发射断层扫描对嗜铬细胞瘤和副神经节瘤的分期和功能特征分析。
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通过Ga-68 DOTANOC正电子发射断层扫描-计算机断层扫描偶然诊断出多发副神经节瘤

Incidental Diagnosis of Multiple Paragangliomas by Ga-68 DOTANOC Positron Emission Tomography-Computed Tomography.

作者信息

Saini Vivek Kumar, Kumar Akshay, Nazar Aftab Hasan, Ora Manish, Gambhir Sanjay

机构信息

Department of Nuclear Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

出版信息

Asia Ocean J Nucl Med Biol. 2021 Spring;9(2):173-176. doi: 10.22038/AOJNMB.2021.17883.

DOI:10.22038/AOJNMB.2021.17883
PMID:34250146
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8255528/
Abstract

A 65-year-old man presented with intermittent abdominal pain for three months. Abdominal ultrasonography revealed a mass in the body of the pancreas. Moreover, abdominal contrast-enhancing computed tomography revealed a homogenously enhancing mass in the body of the pancreas. Scan findings were in favor of the neuroendocrine tumor, and the serum chromogranin level was slightly raised (111.9 ng/ml, normal <98). He had no history of vomiting, jaundice, melena, hematemesis, constipation, diarrhea, weight gain, weight loss, loss of appetite, and fever. He also had no symptoms related to the excessive production of catecholamines, such as hypertension. The patient was referred for Ga-68 DOTANOC positron emission tomography-computed tomography (Ga-68 DOTANOC PET-CT) for further evaluation. The scan was done to rule out metastatic disease or other synchronous lesions to plan surgical excision. The Ga-68 DOTANOC PET-CT revealed a pancreatic lesion with no other abdominal lesions. We noted multiple tracer avid soft tissue lesions on both sides of the neck that were not diagnosed previously. This case report demonstrates a rare case with multiple paragangliomas diagnosed by the Ga-68 DOTANOC PET-CT. This finding could lead to changes in patient management.

摘要

一名65岁男性因间歇性腹痛3个月前来就诊。腹部超声检查发现胰腺体部有一肿块。此外,腹部增强计算机断层扫描显示胰腺体部有一均匀强化的肿块。扫描结果支持神经内分泌肿瘤的诊断,血清嗜铬粒蛋白水平略有升高(111.9 ng/ml,正常<98)。他没有呕吐、黄疸、黑便、呕血、便秘、腹泻、体重增加、体重减轻、食欲不振和发热的病史。他也没有与儿茶酚胺过度分泌相关的症状,如高血压。该患者被转诊进行Ga-68 DOTANOC正电子发射断层扫描-计算机断层扫描(Ga-68 DOTANOC PET-CT)以进一步评估。进行该扫描是为了排除转移性疾病或其他同步病变,以便计划手术切除。Ga-68 DOTANOC PET-CT显示胰腺有病变,腹部无其他病变。我们注意到颈部两侧有多个摄取示踪剂的软组织病变,这些病变以前未被诊断出来。本病例报告展示了一例通过Ga-68 DOTANOC PET-CT诊断出多发副神经节瘤的罕见病例。这一发现可能会导致患者治疗方案的改变。