Saini Vivek Kumar, Kumar Akshay, Nazar Aftab Hasan, Ora Manish, Gambhir Sanjay
Department of Nuclear Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Asia Ocean J Nucl Med Biol. 2021 Spring;9(2):173-176. doi: 10.22038/AOJNMB.2021.17883.
A 65-year-old man presented with intermittent abdominal pain for three months. Abdominal ultrasonography revealed a mass in the body of the pancreas. Moreover, abdominal contrast-enhancing computed tomography revealed a homogenously enhancing mass in the body of the pancreas. Scan findings were in favor of the neuroendocrine tumor, and the serum chromogranin level was slightly raised (111.9 ng/ml, normal <98). He had no history of vomiting, jaundice, melena, hematemesis, constipation, diarrhea, weight gain, weight loss, loss of appetite, and fever. He also had no symptoms related to the excessive production of catecholamines, such as hypertension. The patient was referred for Ga-68 DOTANOC positron emission tomography-computed tomography (Ga-68 DOTANOC PET-CT) for further evaluation. The scan was done to rule out metastatic disease or other synchronous lesions to plan surgical excision. The Ga-68 DOTANOC PET-CT revealed a pancreatic lesion with no other abdominal lesions. We noted multiple tracer avid soft tissue lesions on both sides of the neck that were not diagnosed previously. This case report demonstrates a rare case with multiple paragangliomas diagnosed by the Ga-68 DOTANOC PET-CT. This finding could lead to changes in patient management.
一名65岁男性因间歇性腹痛3个月前来就诊。腹部超声检查发现胰腺体部有一肿块。此外,腹部增强计算机断层扫描显示胰腺体部有一均匀强化的肿块。扫描结果支持神经内分泌肿瘤的诊断,血清嗜铬粒蛋白水平略有升高(111.9 ng/ml,正常<98)。他没有呕吐、黄疸、黑便、呕血、便秘、腹泻、体重增加、体重减轻、食欲不振和发热的病史。他也没有与儿茶酚胺过度分泌相关的症状,如高血压。该患者被转诊进行Ga-68 DOTANOC正电子发射断层扫描-计算机断层扫描(Ga-68 DOTANOC PET-CT)以进一步评估。进行该扫描是为了排除转移性疾病或其他同步病变,以便计划手术切除。Ga-68 DOTANOC PET-CT显示胰腺有病变,腹部无其他病变。我们注意到颈部两侧有多个摄取示踪剂的软组织病变,这些病变以前未被诊断出来。本病例报告展示了一例通过Ga-68 DOTANOC PET-CT诊断出多发副神经节瘤的罕见病例。这一发现可能会导致患者治疗方案的改变。