ANS Clinic, Neuro Praxis Düsseldorf, Düsseldorf, Germany.
Praxis f. Kardiologie & Amb. Herzkatheterkooperation Bonn, Im Mühlenbach 2 B, 53127, Bonn, Germany.
Herzschrittmacherther Elektrophysiol. 2021 Sep;32(3):335-340. doi: 10.1007/s00399-021-00779-y. Epub 2021 Jul 12.
Patients with primary neurogenic disorders such as pure autonomic failure or multiple system atrophy may initially present with cardiocirculatory symptoms such as orthostatic intolerance or fluctuations in heart rate with symptomatic tachycardia. It is therefore clinically important to identify such patients since circulatory manifestations are only one of a series of symptoms resulting from autonomic dysfunction in various organ systems. These patients require a multimodal diagnostic and therapeutic approach and should undergo extensive evaluation in a specialized autonomic nervous system (ANS) outpatient unit. Based on a clinical case presentation, the current review summarizes the diagnostic and therapeutic approach to key cardiovascular symptoms of primary autonomic disorders and their neurological work-up in a specialized autonomic function laboratory.
患有原发性神经源性疾病（如单纯自主神经衰竭或多系统萎缩）的患者最初可能会出现心血管症状，如直立不耐受或心率波动伴症状性心动过速。因此，识别这些患者具有重要的临床意义，因为循环表现只是各种器官系统自主功能障碍引起的一系列症状之一。这些患者需要多模式诊断和治疗方法，并应在专门的自主神经系统（ANS）门诊单位进行广泛评估。基于临床病例介绍，本综述总结了原发性自主神经障碍的关键心血管症状的诊断和治疗方法，以及在专门的自主功能实验室中的神经学检查。
