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瑞典婴儿猝死综合征及无生命体征发作的流行病学

The epidemiology of sudden infant death syndrome and attacks of lifelessness in Sweden.

作者信息

Wennergren G, Milerad J, Lagercrantz H, Karlberg P, Svenningsen N W, Sedin G, Andersson D, Grögaard J, Bjure J

机构信息

Department of Paediatrics I, Gothenburg University, Sweden.

出版信息

Acta Paediatr Scand. 1987 Nov;76(6):898-906. doi: 10.1111/j.1651-2227.1987.tb17261.x.

DOI:10.1111/j.1651-2227.1987.tb17261.x
PMID:3425307
Abstract

Infants who died showing the syndrome of sudden infant death (SIDS) and infants who survived attacks of lifelessness (AL) were examined in a prospective epidemiological multicentre study over 24 months covering close to 40% of all births in Sweden. Seventy SIDS cases and 34 cases of AL were observed, giving an incidence for SIDS of 0.94/1000 and for AL of 0.46/1000. This SIDS incidence is higher than that observed during the seventies. The boy/girl ratio was 1.4:1 for SIDS and 1.6:1 for AL. The age distribution for AL resembled that for SIDS. Similarities were also seen with regard to place of occurrence. Sixty per cent of the SIDS cases occurred during the daytime/evening. Twenty-nine per cent of the infants with AL had more than one apneic spell during the three-day-period around the attack, indicating a period of respiratory instability, but only 12% had such spells later on. None of the infants who had had AL died from SIDS. The possible relationship between AL and SIDS is discussed.

摘要

在一项为期24个月的前瞻性多中心流行病学研究中,对死于婴儿猝死综合征(SIDS)的婴儿以及经历无生命体征发作(AL)后存活的婴儿进行了检查,该研究覆盖了瑞典近40%的出生人口。观察到70例SIDS病例和34例AL病例,SIDS的发病率为0.94/1000,AL的发病率为0.46/1000。该SIDS发病率高于七十年代观察到的发病率。SIDS的男/女比例为1.4:1,AL为1.6:1。AL的年龄分布与SIDS相似。在发生地点方面也观察到相似之处。60%的SIDS病例发生在白天/晚上。29%的AL婴儿在发作前三天内有不止一次呼吸暂停发作,表明存在呼吸不稳定期,但之后只有12%的婴儿有此类发作。所有经历过AL的婴儿均未死于SIDS。文中讨论了AL与SIDS之间可能的关系。

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