中隔去传入神经支配会在大鼠海马体中产生持续的节律性慢活动（θ波）。

Septal deafferentation produces continuous rhythmic slow activity (theta) in the rat hippocampus.

作者信息

Kvirkvelia L, Buzsáki G, Grastyán E

机构信息

Institute of Physiology, University Medical School, Pécs, Hungary.

出版信息

Acta Physiol Hung. 1987;70(1):127-31.

PMID:3425327

Abstract

Hippocampal EEG was recorded in behaving rats in which the brain stem afferents to the septal region were previously damaged. In these animals rhythmic slow activity (RSA or theta) was continuously present, including drinking and immobility. The average frequency of RSA, however, was significantly higher during running (8-9 Hz) than during drinking or awake motionless state (6-8 Hz). In normal rats irregular sharp waves, rather than RSA were present during drinking and immobility. The results suggest that brain stem afferents are necessary to suppress the rhythmic firing of septal "pacemaker" cells.

摘要

在行为学实验大鼠中记录海马脑电图，这些大鼠先前已损伤了到隔区的脑干传入神经。在这些动物中，包括饮水和静止不动时，节律性慢活动（RSA或θ波）持续存在。然而，RSA的平均频率在奔跑时（8 - 9赫兹）显著高于饮水或清醒静止状态时（6 - 8赫兹）。在正常大鼠中，饮水和静止不动时出现的是不规则锐波，而非RSA。结果表明，脑干传入神经对于抑制隔区“起搏器”细胞的节律性放电是必要的。