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钝性创伤后双侧颈内动脉和左侧椎动脉夹层:一例报告及文献综述

Bilateral Internal Carotid and Left Vertebral Artery Dissection after Blunt Trauma: A Case Report and Literature Review.

作者信息

Ariyada Kenichi, Shibahashi Keita, Hoda Hidenori, Watanabe Shinta, Nishida Masahiro, Hanakawa Kazuo, Murao Masahiko

机构信息

Department of Neurosurgery, Tokyo Metropolitan Bokutoh Hospital.

Department of Emergency and Critical Care Center, Tokyo Metropolitan Bokutoh Hospital.

出版信息

Neurol Med Chir (Tokyo). 2019 Apr 15;59(4):154-161. doi: 10.2176/nmc.cr.2018-0239. Epub 2019 Mar 16.

Abstract

Multi-vessel cervical arterial injury after blunt trauma is rare, and its pathophysiology is unclear. Although blunt cerebrovascular injury is a common cause of cerebral ischemia, its management is still controversial. We describe a 23-year-old man in previously good health who developed three-vessel cervical arterial dissections due to blunt trauma. He was admitted to our emergency and critical care center after a motor vehicle crash. Computed tomography showed a thin, acute subdural hematoma in the right hemisphere and fractures of the odontoid process (Anderson type III), pelvis, and extremities. He was treated conservatively, and about 1 month later, he developed bleariness. Computed tomography angiography showed bilateral internal carotid and left vertebral artery dissection. Aspirin therapy was started immediately, and then clopidogrel was added to the regimen. Two weeks later, magnetic resonance angiography (MRA) showed improved blood flow of the vessels. Only aspirin therapy was continued. About 3 months after discharge, MRA demonstrated further improvement of the blood flow of both internal carotid arteries, but the dissection flap on the right side remained. Therefore, we extended the duration of antiplatelet therapy. On the basis of our experience with this case, we think that antithrombotic therapy is crucial for the management of multi-vessel cervical arterial injury, and agents should be used properly according to the injury grade and phase; however, further study is needed to confirm this recommendation.

摘要

钝性创伤后多支颈动脉损伤较为罕见,其病理生理学尚不清楚。尽管钝性脑血管损伤是脑缺血的常见原因,但其治疗仍存在争议。我们描述了一名23岁身体健康的男性,因钝性创伤导致三支颈动脉夹层形成。他在机动车碰撞后被送入我们的急诊与重症监护中心。计算机断层扫描显示右半球有薄层急性硬膜下血肿,齿突(安德森III型)、骨盆和四肢骨折。他接受了保守治疗,大约1个月后,他出现视物模糊。计算机断层扫描血管造影显示双侧颈内动脉和左侧椎动脉夹层。立即开始阿司匹林治疗,随后在治疗方案中加入氯吡格雷。两周后,磁共振血管造影(MRA)显示血管血流改善。仅继续使用阿司匹林治疗。出院后约3个月,MRA显示双侧颈内动脉血流进一步改善,但右侧夹层瓣仍存在。因此,我们延长了抗血小板治疗的持续时间。基于我们对该病例的经验,我们认为抗栓治疗对于多支颈动脉损伤的管理至关重要,应根据损伤分级和阶段正确使用药物;然而,需要进一步研究来证实这一建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09de/6465530/83673607900c/nmc-59-154-g1.jpg

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