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本文引用的文献

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Effects of COVID-19 on Parkinson's Disease Clinical Features: A Community-Based Case-Control Study.新冠疫情对帕金森病临床特征的影响：一项基于社区的病例对照研究。
Mov Disord. 2020 Aug;35(8):1287-1292. doi: 10.1002/mds.28170. Epub 2020 Jun 11.
2
A Post-COVID-19 Parkinsonism in the Future?未来会出现新冠后帕金森综合征吗？
Mov Disord. 2020 Jul;35(7):1094. doi: 10.1002/mds.28117. Epub 2020 May 21.
3
What can Parkinson's disease teach us about COVID-19?帕金森病能让我们对新冠病毒有哪些了解？
Neurol Neurochir Pol. 2020;54(2):204-206. doi: 10.5603/PJNNS.a2020.0039. Epub 2020 Apr 23.
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Clinical and immunological features of severe and moderate coronavirus disease 2019.新型冠状病毒病 2019 重症和中度患者的临床和免疫学特征。
J Clin Invest. 2020 May 1;130(5):2620-2629. doi: 10.1172/JCI137244.
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Parkinsonism and neurological manifestations of influenza throughout the 20th and 21st centuries.20 世纪至 21 世纪期间流感引发的帕金森病及神经学表现。
Parkinsonism Relat Disord. 2010 Nov;16(9):566-71. doi: 10.1016/j.parkreldis.2010.06.012. Epub 2010 Jul 21.
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Understanding the mechanism of action of the anti-influenza virus drug amantadine.了解抗流感病毒药物金刚烷胺的作用机制。
Trends Microbiol. 1995 Jul;3(7):271. doi: 10.1016/s0966-842x(00)88942-8.

一名帕金森病患者感染新冠病毒后的病情恶化

Post-COVID worsening of a Parkinson's disease patient.

作者信息

Boika Aliaksandr V, Sialitski Mikhail M, Chyzhyk Veranika A, Ponomarev Vladimir V, Fomina Elena G

机构信息

Department of Neurology and Neurosurgery Belarusian Medical Academy of Postgraduate Education Minsk Republic of Belarus.

The Republican Research and Practical Center for Epidemiology & Microbiology (RRPCM) Minsk Republic of Belarus.

出版信息

Clin Case Rep. 2021 Jul 6;9(7):e04409. doi: 10.1002/ccr3.4409. eCollection 2021 Jul.

DOI:10.1002/ccr3.4409
PMID:34257979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8259921/
Abstract

Worsening of clinical symptoms after COVID-19 infection and misregulation of CD4 and CD8 T-cell numbers may be revealed in PD patients. Immunological changes may be a source of clinical worsening of the patient.

摘要

在帕金森病（PD）患者中，可能会出现新冠病毒感染（COVID-19）后临床症状恶化以及CD4和CD8 T细胞数量的调节异常。免疫变化可能是患者临床症状恶化的一个原因。