Priya Lakshmi, Moorthy Bini
Department of Psychiatry, University of Missouri-Kansas City School of Medicine, 2411 Holmes Street Kansas City, MO 64108, USA.
Case Rep Psychiatry. 2021 Jun 24;2021:5557211. doi: 10.1155/2021/5557211. eCollection 2021.
Aripiprazole is an antipsychotic with partial agonist activity at the dopamine D2 receptor which may lead to compulsive behaviors including hypersexuality. The case presented is of a 24-year-old male with schizophrenia who developed hypersexuality symptoms after initiation of aripiprazole. Cessation of the aripiprazole led to a reduction in hypersexual behaviors. Clinicians should be aware of compulsive behaviors including hypersexuality with aripiprazole use and consider discontinuation of aripiprazole treatment in patients suffering from hypersexuality.
阿立哌唑是一种抗精神病药物,对多巴胺D2受体具有部分激动剂活性,可能导致包括性欲亢进在内的强迫行为。本文介绍的病例是一名24岁的精神分裂症男性患者,在开始使用阿立哌唑后出现了性欲亢进症状。停用阿立哌唑后,性欲亢进行为有所减少。临床医生应意识到使用阿立哌唑可能出现包括性欲亢进在内的强迫行为,并考虑对患有性欲亢进的患者停用阿立哌唑治疗。