觉醒期缺血性卒中患者的快速眼动（REM）睡眠微结构改变：一项多导睡眠图研究。
Rapid eye movement (REM) sleep microarchitecture is altered in patients with wake-up ischemic stroke: A polysomnographic study.
作者信息
Mekky Jaidaa, El-Kholy Osama, Hamdy Eman, Fawzy Akram
机构信息
Department of Neuropsychiatry, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
出版信息
Neurobiol Sleep Circadian Rhythms. 2021 Jun 23;11:100069. doi: 10.1016/j.nbscr.2021.100069. eCollection 2021 Nov.
UNLABELLED
It is well established that certain alteration of sleep disorders occur in patients with wake-up stroke (WUS) such as sleep disordered breathing, periodic limb movements and sleep duration. However, the data are lacking about the microarchitecture of different sleep stages among those patients.
AIM OF WORK
To compare the polysomnographic microarchitecture of rapid eye movement (REM) sleep between WUS and daytime stroke (DTS).
METHODS
A cross-sectional polysomnographic study was conducted on 20 patients with WUS and 20 patients with DTS, with analysis of REM sleep microarchitecture in specific.
RESULTS
Patients with WUS had significantly shorter REM stage (11.76 ± 5.48% in WUS versus 16.59 ± 5.33% in DTS, P = 0.008), longer early morning REM was (25.70 ± 13.13 min in WUS versus 4.15 ± 4.69 min in DTS, P=<0.001), higher apnea-hypopnea index (AHI) during REM (6.29 ± 10.18 in WUS versus 1.10 ± 4.57 in DTS, P = 0.009), and lower mean Oxygen saturation during REM (92.70 ± 3.63 WUS versus 95.45 ± 1.35 DTS, P = 0.012). The OR of early morning REM duration was 1.8 (CI 1.099-3.130, p = 0.021) for WUS.
CONCLUSION
The microarchitecture of REM sleep is disrupted in patients with wake-up stroke.
未标注
众所周知，觉醒性卒中（WUS）患者会出现某些睡眠障碍改变，如睡眠呼吸紊乱、周期性肢体运动和睡眠时间。然而，这些患者不同睡眠阶段的微观结构数据尚缺。
工作目的
比较觉醒性卒中（WUS）和日间卒中（DTS）患者快速眼动（REM）睡眠的多导睡眠图微观结构。
方法
对20例WUS患者和20例DTS患者进行横断面多导睡眠图研究，特别分析REM睡眠微观结构。
结果
WUS患者的REM期明显较短（WUS为11.76±5.48%，DTS为16.59±5.33%，P = 0.008），清晨REM期较长（WUS为25.70±13.13分钟，DTS为4.15±4.69分钟，P<0.001），REM期呼吸暂停低通气指数（AHI）较高（WUS为6.29±10.18，DTS为1.10±4.57，P = 0.009），REM期平均血氧饱和度较低（WUS为92.70±3.63，DTS为95.45±1.35，P = 0.012）。WUS患者清晨REM持续时间的OR为1.8（CI 1.099 - 3.130，p = 0.021）。
结论
觉醒性卒中患者的REM睡眠微观结构受到破坏。
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