Department of Gynecologic Surgery, Mayo Clinic Arizona, Phoenix, Arizona.
Mayo Clinic Arizona Investigational Pharmacy Services, Phoenix, Arizona.
J Opioid Manag. 2021 May-Jun;17(3):189-194. doi: 10.5055/jom.2021.0629.
Currently, in the United States, there is an epidemic of opioid abuse. While this problem is well known to the public due to significant media and political attention, patients are poorly educated on the proper handling and disposal of unused opioids. Instead, the onus has fallen on the healthcare provider to minimize the number of opioids prescribed.
To improve proper opioid disposal rates after gynecologic surgery by providing educational materials along with a disposal bag.
We performed a prospective study evaluating baseline understanding of medication disposal using a questionnaire given to the patients during their preoperative visit. Subsequently, patients were provided written information on proper disposal of their medications and an activated charcoal medication disposal bag. Study patients completed a survey about disposal of their unused opioids at their last post-operative visit. The success of education and proper disposal of opioid medications were evaluated.
Thirty-five patients, average age of 45 (range 20-77), were enrolled, and 31 patients successfully completed both surveys. The surgeries performed included hysterectomy 23 percent (n = 7), laparoscopic excision of endometriosis 32 percent (n = 10), laparoscopic ovarian cystectomy 23 percent (n = 7), prolapse repair 3 percent (n = 1), and midurethral sling procedures 19 percent (n = 6). Chronic pelvic pain was identified in 39 percent (n = 12) of our patient population. Prior to education, 52 percent (n = 16) of patients did not dispose of their opioids. Furthermore, 71 percent (n = 22) of patients stated they had never been educated by a medical provider regarding appropriate disposal. Nineteen percent (n = 6) confirmed they have used an opioid medication prescribed to someone else. Demographic data show 65 percent (n = 20) of these patients had completed a college degree or greater. After education and being given a reliable option for medication disposal with the Deterra® bag, 94 percent (n = 29) of patients properly disposed of their opioids after surgery, demonstrating a 45 percent (p < 0.001) increase in proper disposal. In our study alone, 491 tablets of 5mg oxycodone were properly disposed. The majority of patients, 77 percent (n = 24) used the drug disposal bag, and when queried, stated they would be willing to pay on average $7.70 (range 0-20) per bag. Without education and a simple option for disposal, 422 tablets prescribed may have been subject to inappropriate diversion.
This study clearly shows that patient education, coupled with a reliable option for opioid disposal, is effective. We strongly encourage other surgical institutions to implement similar practices not only for our surgical patients' safety, but also for the tens of thousands of patients who died of opioid abuse in the last year.
目前,在美国,阿片类药物滥用已成流行趋势。尽管由于媒体和政治的广泛关注,公众对此问题已有所了解,但患者对未使用的阿片类药物的正确处理和处置方式仍缺乏认知。相反,医疗服务提供者的职责是尽量减少开具的阿片类药物数量。
通过提供教育材料和处置袋,提高妇科手术后正确处理阿片类药物的比例。
我们进行了一项前瞻性研究,通过在患者术前就诊时进行问卷调查,评估他们对药物处置的基本理解。随后,向患者提供有关正确处置药物的书面信息和已激活的活性炭药物处置袋。研究患者在最后一次术后就诊时完成了一份关于未使用阿片类药物处置情况的调查。评估教育和阿片类药物正确处置的效果。
共纳入 35 名平均年龄为 45 岁(范围 20-77 岁)的患者,其中 31 名患者成功完成了两次调查。所进行的手术包括子宫切除术 23%(n=7)、腹腔镜子宫内膜异位症切除术 32%(n=10)、腹腔镜卵巢囊肿切除术 23%(n=7)、脱垂修复术 3%(n=1)和中尿道吊带手术 19%(n=6)。我们的患者群体中有 39%(n=12)存在慢性盆腔疼痛。在接受教育之前,52%(n=16)的患者没有处理他们的阿片类药物。此外,71%(n=22)的患者表示他们从未接受过医疗服务提供者关于适当处置的教育。19%(n=6)的患者确认他们曾将他人开的阿片类药物用于自己。人口统计学数据显示,这些患者中有 65%(n=20)完成了大学或更高学历。经过教育并提供可靠的药物处置选择(Deterra®袋)后,94%(n=29)的患者在手术后正确处理了他们的阿片类药物,表明正确处置的比例增加了 45%(p<0.001)。仅在我们的研究中,就正确处置了 491 片 5mg 羟考酮。大多数患者(n=24)使用了药物处置袋,当被问及是否愿意为此付费时,他们平均表示愿意支付 7.70 美元(范围 0-20 美元)一个袋子。如果没有教育和简单的处置选择,可能有 422 片规定的阿片类药物会被不当转移。
这项研究清楚地表明,患者教育加上可靠的阿片类药物处置选择是有效的。我们强烈鼓励其他外科医疗机构实施类似的做法,不仅为了我们外科患者的安全,也为了去年因阿片类药物滥用而死亡的成千上万的患者。