Rottnek Fred
SSM Health/Saint Louis University School of Medicine, Family and Community Medicine, St. Louis, Missouri, USA.
Innov Aging. 2025 May 6;9(6):igaf040. doi: 10.1093/geroni/igaf040. eCollection 2025.
The management of pain in older adults has been profoundly shaped by shifting attitudes toward acute and chronic opioid therapy. Historically, opioids have been recognized as highly effective for acute and cancer-related pain, but their use in chronic non-cancer pain, especially among older adults, remains controversial due to concerns about addiction, safety, and efficacy. Over recent decades, increased opioid prescribing has coincided with a dramatic rise in opioid misuse, addiction, and overdose deaths, prompting renewed scrutiny of prescribing practices and regulatory responses. This article traces the historical "pendulum" of opioid policy and practice, examines the unique challenges faced by older adults-including heightened vulnerability to adverse effects and polypharmacy-and highlights the ongoing debate between ensuring adequate pain relief and minimizing harm. It also explores best practices and emerging approaches, such as patient-centered care and the integration of non-opioid therapies, and calls for a balanced, evidence-based framework that addresses both the legitimate needs of older adults in pain and the societal imperative to reduce opioid-related harms.
对急性和慢性阿片类药物治疗态度的转变深刻影响了老年人疼痛的管理。从历史上看,阿片类药物已被公认为对急性疼痛和癌症相关疼痛非常有效,但由于对成瘾、安全性和有效性的担忧,它们在慢性非癌性疼痛中的使用,尤其是在老年人中,仍然存在争议。近几十年来,阿片类药物处方量的增加与阿片类药物滥用、成瘾和过量死亡的急剧上升同时出现,促使人们重新审视处方做法和监管对策。本文追溯了阿片类药物政策和实践的历史“钟摆”,审视了老年人面临的独特挑战——包括对不良反应和多重用药的更高易感性——并强调了在确保充分缓解疼痛和尽量减少伤害之间持续存在的争论。它还探讨了最佳实践和新兴方法,如以患者为中心的护理和非阿片类疗法的整合,并呼吁建立一个平衡的、基于证据的框架,以满足疼痛老年人的合理需求以及减少阿片类药物相关危害的社会要求。