Chen Zhao-Xia, Li Ping, Zhang Guang-Zhong, Li Bo, Hu Jing, Feng Shuo, Li Bo-Hua, Lv Jing-Jing, Guo Xin-Wei, Zhao Jing-Xia, Di Ting-Ting, Feng Fang, Wang Yan
Beijing Key Laboratory of Clinic and Basic Research with TCM on Psoriasis, Beijing Institute of TCM, Capital Medical University, Beijing 100010, China.
Department of Dermatology, Beijing Hospital of TCM, Capital Medical University, Beijing 100010, China.
Zhongguo Zhen Jiu. 2021 Jul 12;41(7):762-6. doi: 10.13703/j.0255-2930.20200907-0004.
To observe the short-term and long-term effects of moxibustion on plaque psoriasis of blood stasis, and to compare the curative effect between moxibustion and calcipotriol ointment.
A total of 80 patients with plaque psoriasis of blood stasis were randomly divided into an observation group (40 cases, 2 cases dropped off) and a control group (40 cases, 4 cases dropped off). Both groups were given routine medical vaseline topical emollient basic treatment. In the observation group, moxibustion was applied to point (target skin lesions), Zusanli (ST 36), Xuehai (SP 10) and Qihai (CV 6) for 30 min each time, 3 times a week. The control group was treated with calcipotriol ointment (0.25 g each time, once in the morning and evening) on the target skin lesions. Both groups were treated for 8 weeks. The psoriasis area and severity index (PASI) score before and after treatment, main clinical symptoms of TCM score and dermatology life quality index (DLQI) score before and after treatment and 3 and 6 moths follow-up were observed in the two groups; the clinical efficacy after treatment was evaluated and the recurrence rates of the two groups were followed up for 3 and 6 months after treatment.
After treatment, the PASI scores in the both groups were lower than before treatment (<0.01). After treatment and 3 and 6 months follow-up, the main clinical symptoms of TCM scores and DLQI scores of the two groups were lower than those before treatment (<0.05), and at 3 and 6 months follow-up, those in the observation group were lower than the control group (<0.01). There was no statistically significant difference between the observation group and the control group in overall effective rate and target skin lesion effective rate (>0.05). At 3 and 6 months follow-up, the overall recurrence rate and target skin lesion recurrence rate in the observation group were lower than those in the control group (<0.05).
Both moxibustion and calcipotriol ointment have good short-term effects on plaque psoriasis of blood stasis. Moxibustion has more advantages in reducing the recurrence rate of psoriasis, improving the main clinical symptoms of TCM and quality of life.
观察艾灸对血瘀型斑块状银屑病的近期及远期疗效，并比较艾灸与卡泊三醇软膏的疗效。
将80例血瘀型斑块状银屑病患者随机分为观察组（40例，脱落2例）和对照组（40例，脱落4例）。两组均给予常规医用凡士林外用润肤基础治疗。观察组在阿是穴（靶皮损处）、足三里（ST36）、血海（SP10）、气海（CV6）行艾灸，每次30分钟，每周3次。对照组在靶皮损处外用卡泊三醇软膏（每次0.25g，早晚各1次）。两组均治疗8周。观察两组治疗前后银屑病面积和严重程度指数（PASI）评分、中医主要临床症状评分及治疗前后和治疗后3、6个月随访的皮肤病生活质量指数（DLQI）评分；评估治疗后临床疗效，并随访两组治疗后3、6个月的复发率。
治疗后，两组PASI评分均低于治疗前（P<0.01）。治疗后及治疗后3、6个月随访，两组中医主要临床症状评分及DLQI评分均低于治疗前（P<0.05），且治疗后3、6个月随访时，观察组低于对照组（P<0.01）。观察组与对照组总有效率及靶皮损有效率比较，差异无统计学意义（P>0.05）。治疗后3、6个月随访，观察组总复发率及靶皮损复发率均低于对照组（P<0.05）。
艾灸与卡泊三醇软膏对血瘀型斑块状银屑病均有良好的近期疗效。艾灸在降低银屑病复发率、改善中医主要临床症状及生活质量方面更具优势。
