Olah I, Glick B
Poultry Science Department, Mississippi Agricultural and Forestry Experiment Station, Mississippi State University 39762.
Anat Rec. 1987 Nov;219(3):268-74. doi: 10.1002/ar.1092190307.
In addition to lymphocytes, macrophages, and epithelial cells, the bursa medulla possesses a cell we have named the secretory cell. The secretory cell, which makes up approximately 0.5% of the bursal cell population, exhibits an eccentric nucleus with a chromatin pattern similar to that of a small lymphocyte and an elongated cytoplasm with one or more cell processes. The electron-dense cytoplasmic granules of the immature secretory cell are localized around the cytocentrum, while in the mature secretory cell these granules are situated beneath the cell membrane of one process. The granular location endows a polarized appearance to the secretory cell. The surface of the membrane is covered with a finely spotted flocculated substance, which may originate from a granular discharge. The round, ovoid, or irregular-shaped granules reveal a homogeneous or distinctive internal pattern. The cortico-medullary border may be the germinal layer of the bursal medulla. The bursal secretory cell is a modified dendritic cell with possible endocrine functions that may be important in B-cell induction.
除淋巴细胞、巨噬细胞和上皮细胞外，法氏囊髓质还有一种我们命名为分泌细胞的细胞。分泌细胞约占法氏囊细胞总数的0.5%，其细胞核偏心，染色质模式与小淋巴细胞相似，细胞质细长，有一个或多个细胞突起。未成熟分泌细胞的电子致密细胞质颗粒位于细胞中心周围，而在成熟分泌细胞中，这些颗粒位于一个突起的细胞膜下方。颗粒的位置赋予了分泌细胞一种极化外观。细胞膜表面覆盖着一种细小斑点状的絮凝物质，可能源自颗粒排放。圆形、卵形或不规则形状的颗粒呈现出均匀或独特的内部模式。皮质-髓质边界可能是法氏囊髓质的生发层。法氏囊分泌细胞是一种经过修饰的树突状细胞，可能具有内分泌功能，这在B细胞诱导中可能很重要。
