Leppert J, Aberg H, Ringqvist I, Sörensson S
Department of Family Medicine, Akademiska Sjukhuset, Uppsala, Sweden.
Angiology. 1987 Dec;38(12):871-7. doi: 10.1177/000331978703801201.
In a random sample of 3000 women of ages eighteen to fifty-nine years in the city of Västerås, Sweden, 19% of the 2705 responders to a questionnaire complained of cold and white fingers with or without numbness. On the basis of interview and examination, 79% of these women were diagnosed as having Raynaud's phenomenon (RP), giving a prevalence of 15.6%. A significantly higher rate of family members with cold, white fingers was found only in the group of women with pronounced RP (p less than 0.001). A significantly higher frequency of women with pronounced RP than of the control group had a history of recurrent muscle/joint pain (p less than 0.05). Laboratory tests that might indicate an active connective tissue disease did not, however, confirm a diagnosis of rheumatoid arthritis. All three subgroups differed significantly from the control group in terms of recurrent chest pains; subgroups 2 and N differed significantly from controls in terms of recurrent headaches.
在瑞典韦斯特罗斯市随机抽取的3000名年龄在18至59岁之间的女性样本中，在对问卷做出回应的2705人中，19%的人抱怨手指发冷、发白，伴有或不伴有麻木感。根据访谈和检查，这些女性中有79%被诊断为患有雷诺现象（RP），患病率为15.6%。仅在患有明显RP的女性组中发现家庭成员手指发冷、发白的比例明显更高（p小于0.001）。与对照组相比，患有明显RP的女性复发性肌肉/关节疼痛病史的频率明显更高（p小于0.05）。然而，可能表明存在活动性结缔组织病的实验室检查并未确诊类风湿性关节炎。在复发性胸痛方面，所有三个亚组与对照组均有显著差异；在复发性头痛方面，第2亚组和N亚组与对照组有显著差异。
