Drake Connor, Lian Tyler, Trogdon Justin G, Edelman David, Eisenson Howard, Weinberger Morris, Reiter Kristin, Shea Christopher M
Department of Population Health Sciences, Duke University School of Medicine, 215 Morris Street, Durham, NC, 27701, USA.
Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 135 Dauer Dr, Chapel Hill, NC, 27519, USA.
BMC Cardiovasc Disord. 2021 Jul 14;21(1):342. doi: 10.1186/s12872-021-02149-5.
Health systems are increasingly using standardized social needs screening and response protocols including the Protocol for Responding to and Assessing Patients' Risks, Assets, and Experiences (PRAPARE) to improve population health and equity; despite established relationships between the social determinants of health and health outcomes, little is known about the associations between standardized social needs assessment information and patients' clinical condition.
In this cross-sectional study, we examined the relationship between social needs screening assessment data and measures of cardiometabolic clinical health from electronic health records data using two modelling approaches: a backward stepwise logistic regression and a least absolute selection and shrinkage operation (LASSO) logistic regression. Primary outcomes were dichotomized cardiometabolic measures related to obesity, hypertension, and atherosclerotic cardiovascular disease (ASCVD) 10-year risk. Nested models were built to evaluate the utility of social needs assessment data from PRAPARE for risk prediction, stratification, and population health management.
Social needs related to lack of housing, unemployment, stress, access to medicine or health care, and inability to afford phone service were consistently associated with cardiometabolic risk across models. Model fit, as measured by the c-statistic, was poor for predicting obesity (logistic = 0.586; LASSO = 0.587), moderate for stage 1 hypertension (logistic = 0.703; LASSO = 0.688), and high for borderline ASCVD risk (logistic = 0.954; LASSO = 0.950).
Associations between social needs assessment data and clinical outcomes vary by cardiometabolic condition. Social needs assessment data may be useful for prospectively identifying patients at heightened cardiometabolic risk; however, there are limits to the utility of social needs data for improving predictive performance.
卫生系统越来越多地使用标准化的社会需求筛查和应对方案,包括《患者风险、资产和经历应对与评估协议》(PRAPARE),以改善人群健康和公平性;尽管健康的社会决定因素与健康结果之间已确立了关系,但对于标准化社会需求评估信息与患者临床状况之间的关联却知之甚少。
在这项横断面研究中,我们使用两种建模方法,即向后逐步逻辑回归和最小绝对收缩选择算子(LASSO)逻辑回归,研究了社会需求筛查评估数据与电子健康记录数据中的心脏代谢临床健康指标之间的关系。主要结局是与肥胖、高血压和动脉粥样硬化性心血管疾病(ASCVD)10年风险相关的二元心脏代谢指标。构建嵌套模型以评估来自PRAPARE的社会需求评估数据在风险预测、分层和人群健康管理中的效用。
在各个模型中,与住房不足、失业、压力、获得药品或医疗保健的机会以及无力支付电话服务相关的社会需求与心脏代谢风险始终相关。以c统计量衡量的模型拟合度,在预测肥胖方面较差(逻辑回归=0.586;LASSO=0.587),在预测1期高血压方面中等(逻辑回归=0.703;LASSO=0.688),在预测临界ASCVD风险方面较高(逻辑回归=0.954;LASSO=0.950)。
社会需求评估数据与临床结局之间的关联因心脏代谢状况而异。社会需求评估数据可能有助于前瞻性地识别心脏代谢风险较高的患者;然而,社会需求数据在改善预测性能方面的效用存在局限性。