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鼻内用皮质类固醇:患者给药角度及教育的影响

Intranasal Corticosteroids: Patient Administration Angles and Impact of Education.

作者信息

Treat Sara, Ebert Charles S, Farzal Zainab, Basu Saikat, Zanation Adam M, Thorp Brian D, Kimbell Julia S, Senior Brent A, Kimple Adam J

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill.

Marsico Lung Institute at the University of North Carolina at Chapel Hill.

出版信息

Rhinol Online. 2020;3:160-166. doi: 10.4193/rhinol/20.070. Epub 2020 Nov 8.

Abstract

INTRODUCTION

Intranasal corticosteroids sprays (INCS) are first line treatment for allergic rhinitis and are frequently used for chronic rhinosinusitis. Improperly aiming INCS increases the risk of epistaxis and may decrease the efficacy of the medication. The goal of this study was to determine how patients position INCS for drug delivery and if verbal or written instructions improve their positioning.

METHODS

Patients in rhinology clinics were photographed while administering a generic spray bottle. The angle of the spray bottle relative to the patients' head and a fixed background was determined.

RESULTS

A total of 46 participants were included. The average spray angle for the right naris was 10.1° towards the septum and 67.2° below the Frankfurt Horizontal plane. The average spray angle for the left naris was 4.5° towards the septum and 62.2° below the Frankfurt horizontal plane. The angle of the spray bottle ranged from 50° toward the septum to 43° away from the septum. Only 8 patients aimed away from the septum for both nares. Patients who recalled receiving verbal and written instructions aimed the INCS bottle at the lateral wall and inferior turbinate in contrast to patients who only received one form of instruction or no instructions.

CONCLUSIONS

Most patients (83%) incorrectly aim INCS when compared to current guidelines. There was statistically significant improvement in the positioning of patients who reported receiving both verbal and written instruction; however, this study highlights a greater need for patient education.

摘要

引言

鼻内用皮质类固醇喷雾剂(INCS)是变应性鼻炎的一线治疗药物,也常用于慢性鼻-鼻窦炎。使用INCS时喷雾方向不当会增加鼻出血风险,还可能降低药物疗效。本研究的目的是确定患者使用INCS给药时的喷雾方向,以及口头或书面指导是否能改善其喷雾方向。

方法

在鼻科门诊,对患者使用普通喷雾瓶的过程进行拍照。确定喷雾瓶相对于患者头部和固定背景的角度。

结果

共纳入46名参与者。右侧鼻孔的平均喷雾角度是朝向鼻中隔10.1°,低于法兰克福水平面67.2°。左侧鼻孔的平均喷雾角度是朝向鼻中隔4.5°,低于法兰克福水平面62.2°。喷雾瓶的角度范围从朝向鼻中隔50°到远离鼻中隔43°。只有8名患者两个鼻孔的喷雾方向均远离鼻中隔。与仅接受一种形式指导或未接受指导的患者相比,回忆起接受过口头和书面指导的患者将INCS瓶对准外侧壁和下鼻甲。

结论

与当前指南相比,大多数患者(83%)使用INCS时喷雾方向错误。报告同时接受口头和书面指导的患者在喷雾方向上有统计学意义的改善;然而,本研究凸显了加强患者教育的更大必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e8d/8276915/6587c212cbe1/nihms-1675049-f0001.jpg

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