Sezgin Merve Gözde, Bektaş Hicran
Akdeniz University Hospital, Antalya, Turkey.
Department of Internal Medicine Nursing, Akdeniz University Faculty of Nursing, Antalya, Turkey.
Florence Nightingale J Nurs. 2020 Jul 3;28(2):143-154. doi: 10.5152/FNJN.2020.19107. eCollection 2020 Jun.
The study aimed to determine the effect of symptom clustering and its effect on functional status in patients with lymphoma.
This descriptive study was conducted with 109 patients with lymphoma in the Hematology Clinic, Hematology Outpatient Clinic, and Chemotherapy Day Unit of a university hospital. Personal information form, Memorial Symptom Assessment Scale to assess symptoms, and the Functional Assessment of Cancer Therapy-Lymphoma to assess functional status were used in data collection. Frequency, percentage, arithmetic mean, significance test of difference between two means, Mann-Whitney U test, one-way analysis of variance, Kruskal Wallis analysis of variance, Pearson's correlation test, Cronbach's alpha internal consistency test, and cluster analysis were used to evaluate the data.
According to the Memorial Symptom Assessment Scale, the most common psychological symptoms in these patients were sleep disturbance, feeling sad and worried; whereas, their physical symptoms were pain, nausea, and dry mouth. Based on the results of the Functional Assessment of Cancer Therapy-Lymphoma Scale, it was found that the functional lives of the patients were negatively affected due to pain, low energy, feeling sad, worrying about the deterioration of the condition, fatigue and pain in certain parts of the body. In the frequency and severity subscales of Memorial Symptom Assessment Scale, gastrointestinal system symptoms were collected more intensively in the first clusters. Physical and psychological symptoms were regularly distributed in the distress subscale.
As the symptom frequency, severity and distress subscales of Memorial Symptom Assessment Scale increased in lymphoma patients, their functional status deteriorated.
本研究旨在确定淋巴瘤患者症状聚类情况及其对功能状态的影响。
本描述性研究在一所大学医院的血液科门诊、血液科门诊和化疗日间病房对109例淋巴瘤患者进行。数据收集采用个人信息表、用于评估症状的纪念症状评估量表以及用于评估功能状态的癌症治疗功能评估-淋巴瘤量表。采用频率、百分比、算术平均数、两均数差异显著性检验、曼-惠特尼U检验、单因素方差分析、克鲁斯卡尔-沃利斯方差分析、皮尔逊相关检验、克朗巴赫α内部一致性检验和聚类分析对数据进行评估。
根据纪念症状评估量表，这些患者最常见的心理症状是睡眠障碍、悲伤和担忧情绪；而他们的身体症状是疼痛、恶心和口干。根据癌症治疗功能评估-淋巴瘤量表的结果发现，患者的功能生活因疼痛、精力不足、悲伤情绪、担心病情恶化、疲劳以及身体某些部位疼痛而受到负面影响。在纪念症状评估量表的频率和严重程度子量表中，第一组聚类中更集中地收集到了胃肠道系统症状。身体和心理症状在困扰子量表中呈均匀分布。
随着淋巴瘤患者纪念症状评估量表的症状频率、严重程度和困扰子量表得分增加，其功能状态恶化。
