Department of Neurologic Surgery, Regions Hospital, St Paul, Minnesota, USA.
University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Br J Neurosurg. 2024 Feb;38(1):61-67. doi: 10.1080/02688697.2021.1881041. Epub 2021 Jul 15.
A variety of different lumbar spinal fusion techniques have been developed. In this study, we review published medical literature highlighting the differences between lumbar interbody fusion techniques with regard to their surgical technique, clinical outcomes, and complications.
PubMed, ScienceDirect, and Google Scholar searches were performed for studies published between January 1990 to April 2018 reporting spinal fusion surgery clinical outcomes of at least one fusion technique. Clinical outcomes were extracted and pooled by surgical technique. Chi-squared analyses and Fisher Exact Tests were used to determine differences in rates between groups.
PLIF had the highest rate of successful fusion (97% [155/159]) and the lowest rate of complications (4% [6/131]). A chi square analysis revealed a significant difference in fusion success in PLIF compared to PLF (84% [278/330], <.001). PLIF also had significantly fewer complications compared to PSF (14.7% [251/1709], =.001), PLF (13.4% [47/351], =.008), ALIF (14.2% [22/155], =.008), and LIC (13.9% [47/339], =.005). Additionally, there were significant differences in the rate of successful fusion when comparing lateral interbody cage (LIC) techniques (=.041), which include OLIF (100% [63/63]), DLIF (92% [24/26]), and XLIF (87% [67/77]). LIC techniques overall had higher fusion success rates (93.0% [154/166] compared to PLF (=.01), but a higher rate of complications (14% [47/339]) compared to PLIF (=.005) and TLIF (6% [17/259], =.005).
Overall, PLF and XLIF have the lowest fusion success rates, and OLIF demonstrated a trend of higher fusion rates among LIC. Techniques that utilized interbody fusion tended to increase the rate of fusion. While interbody fusion techniques offer higher rates of fusion, complication rates also tend to rise with the increase in complexity of the surgical technique, as with OLIF which notably has the highest fusion rate and complication rate.
已经开发出多种不同的腰椎融合技术。在本研究中,我们回顾了已发表的医学文献,重点介绍了各种腰椎椎间融合技术在手术技术、临床结果和并发症方面的差异。
在 1990 年 1 月至 2018 年 4 月期间,我们在 PubMed、ScienceDirect 和 Google Scholar 上搜索了至少一项融合技术的脊柱融合手术临床结果的研究报告。通过手术技术提取并汇总临床结果。采用卡方分析和 Fisher 精确检验来确定组间差异率。
PLIF 的融合成功率最高(97%[155/159]),并发症发生率最低(4%[6/131])。卡方分析显示,PLIF 与 PLF(84%[278/330],<.001)相比,融合成功率有显著差异。PLIF 与 PSF(14.7%[251/1709],=.001)、PLF(13.4%[47/351],=.008)、ALIF(14.2%[22/155],=.008)和 LIC(13.9%[47/339],=.005)相比,并发症发生率也显著降低。当比较侧方椎间融合 cage(LIC)技术时(=.041),包括 OLIF(100%[63/63])、DLIF(92%[24/26])和 XLIF(87%[67/77]),也存在融合成功率的显著差异。LIC 技术总体上具有更高的融合成功率(93.0%[154/166],与 PLF 相比[=.01]),但并发症发生率(14%[47/339])高于 PLIF([=.005])和 TLIF(6%[17/259],=.005)。
总体而言,PLF 和 XLIF 的融合成功率最低,而 OLIF 显示出 LIC 技术中融合率较高的趋势。使用椎间融合技术的方法往往会增加融合率。虽然椎间融合技术可提高融合率,但随着手术技术复杂性的增加,并发症发生率也会上升,这与 OLIF 相似,OLIF 的融合率和并发症率都很高。