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门诊多学科慢性疼痛管理远程指导服务的临床效果。

Clinical Effectiveness of an Outpatient Multidisciplinary Chronic Pain Management Telementoring Service.

机构信息

Veterans Affairs Northern California Health Care System, Mather, CA.

Pharmacy Outcomes Research Group, Kaiser Permanente National Pharmacy.

出版信息

Clin J Pain. 2021 Oct 1;37(10):740-746. doi: 10.1097/AJP.0000000000000967.

Abstract

OBJECTIVE

The objective of this study was to assess the effectiveness of a Pain E-Consult Program (PEP), a multidisciplinary telementoring service based on the Extension for Community Healthcare Outcomes (ECHO) model to reduce opioid use in the outpatient setting.

MATERIALS AND METHODS

This was a retrospective matched cohort study conducted in an integrated health care delivery system. Adult patients without cancer and with a 90-day morphine milligram equivalent (MME) ≥30 mg/d between April 1, 2016, and June 30, 2017, were included. Patients whose primary care clinician received the PEP (observation) were compared with usual care (control) patients. Observation patients were matched up to 1:5 to control patients. Outcomes included change in MME and initiation of nonopioid alternative medications. Multivariable regression analyses were performed.

RESULTS

A total of 665 patients were matched: 125 and 540 in the observation and control groups, respectively. Patients were primarily female, white, and Medicare beneficiaries. The observation group had a statistically significantly greater decrease in median MME/day during the 6-month (-7.4 vs. 1.5 mg, P=0.002) and 12-month (-15.1 vs. -2.8 mg, P<0.001) follow-up and rates of ≥20% decrease (6 mo: 41.6% vs. 24.6%, P=0.003; 12 mo: 48.0% vs. 32.6%, P=0.017). There were no differences in the rates of initiation of nonopioid alternative medications.

CONCLUSIONS

A PEP was associated with greater reductions in MME/day compared with usual care despite similar rates of nonopioid alternative medication initiation. A prospective randomized study of this program should be undertaken to confirm these findings.

摘要

目的

本研究旨在评估疼痛电子咨询计划(PEP)的有效性,该计划是一种基于扩展社区医疗成果(ECHO)模型的多学科远程指导服务,旨在减少门诊环境中的阿片类药物使用。

材料与方法

这是一项在综合医疗服务提供系统中进行的回顾性匹配队列研究。纳入 2016 年 4 月 1 日至 2017 年 6 月 30 日期间无癌症且 90 天内吗啡毫克当量(MME)≥30mg/d 的成年患者。将接受 PEP(观察组)的初级保健临床医生的患者与常规护理(对照组)患者进行比较。观察组患者与对照组患者的匹配比例为 1:5。主要结局包括 MME 变化和非阿片类替代药物的使用情况。进行多变量回归分析。

结果

共匹配了 665 名患者:观察组和对照组分别为 125 名和 540 名。患者主要为女性、白人、医疗保险受益人。观察组在 6 个月(-7.4 对 1.5mg,P=0.002)和 12 个月(-15.1 对-2.8mg,P<0.001)随访期间的 MME/天中位数下降幅度具有统计学显著意义,且≥20%下降的比例更高(6 个月:41.6%对 24.6%,P=0.003;12 个月:48.0%对 32.6%,P=0.017)。非阿片类替代药物的使用比例没有差异。

结论

与常规护理相比,PEP 与 MME/天的降幅更大,尽管非阿片类替代药物的使用比例相似。应进行该计划的前瞻性随机研究以证实这些发现。

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