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慢性酒精性柯萨科夫综合征患者的临床神经生理学相关性

Clinico-neurophysiological correlations in chronic alcoholic Korsakoff patients.

作者信息

Nickel B, Riedel E

机构信息

Wilhelm Griesinger Hospital, Berlin, GDR.

出版信息

Alcohol Alcohol Suppl. 1987;1:395-9.

PMID:3426707
Abstract

A group of 29 patients with chronic alcoholic KORSAKOFF syndrome (KS) showed a cumulative increase in the interpeak latencies (IPL)I-II to I-VII of the brainstem auditory evoked potentials (BAEP), highest significance with IPL I-VI (p = 7.27 X 10(-6). The KORSAKOFF core group showed higher multiple correlation coefficients R for the IPL than the KS with additional deficiencies of cerebral performance. The BAEP should be used for recording subclinical patterns of brainstem lesions in risk patients with chronic alcoholism.

摘要

一组29例慢性酒精性柯萨科夫综合征(KS)患者的脑干听觉诱发电位(BAEP)中,从I-II到I-VII的峰间潜伏期(IPL)呈累积增加,其中IPL I-VI的差异具有最高显著性(p = 7.27×10⁻⁶)。与存在额外脑功能缺陷的KS患者相比,柯萨科夫核心组的IPL具有更高的多重相关系数R。BAEP应用于记录慢性酒精中毒风险患者脑干病变的亚临床模式。

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