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在对照受试者以及患有韦尼克-科尔萨科夫综合征和多发性硬化症的患者中,对稀疏刺激和密集刺激诱发的脑干听觉诱发电位进行比较。

A comparison of brainstem auditory evoked responses evoked by rarefaction and condensation stimulation in control subjects and in patients with Wernicke-Korsakoff syndrome and multiple sclerosis.

作者信息

Hammond S R, Yiannikas C, Chan Y W

出版信息

J Neurol Sci. 1986 Jul;74(2-3):177-90. doi: 10.1016/0022-510x(86)90103-6.

DOI:10.1016/0022-510x(86)90103-6
PMID:3734836
Abstract

Brainstem auditory evoked responses (BAER) evoked by rarefaction and condensation stimulation were compared in patients with Wernicke-Korsakoff syndrome (WKS) and multiple sclerosis (MS) and click polarity-related differences in topodiagnosis were found in 24% of the WKS and 40% of the MS patients. These results suggest the need to record BAER routinely with both stimulus polarities separately if practicable. BAER from rarefaction and condensation stimulation were recorded from control subjects of both sexes to provide control data for the patient study and also to investigate the interaction between sex and click polarity. BAER latency and amplitude differences between males and females were found to be independent of click polarity. However, the study did show an interaction between female sex and click polarity-related BAER latency differences although differences in amplitude and waveform morphology were essentially independent of sex. This further emphasises the importance of taking into account the variables of sex and stimulus polarity in establishing BAER control values.

摘要

对韦尼克-科尔萨科夫综合征(WKS)和多发性硬化症(MS)患者进行了比较,观察了疏密刺激诱发的脑干听觉诱发电位(BAER),结果发现,24%的WKS患者和40%的MS患者存在与点击极性相关的顶叶诊断差异。这些结果表明,如果可行,有必要分别用两种刺激极性常规记录BAER。记录了来自男女对照组受试者的疏密刺激诱发的BAER,以提供患者研究的对照数据,并研究性别与点击极性之间的相互作用。发现男性和女性之间的BAER潜伏期和振幅差异与点击极性无关。然而,该研究确实显示了女性性别与点击极性相关的BAER潜伏期差异之间存在相互作用,尽管振幅和波形形态的差异基本上与性别无关。这进一步强调了在建立BAER对照值时考虑性别和刺激极性变量的重要性。

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引用本文的文献

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New Perspectives in the Exploration of Korsakoff's Syndrome: The Usefulness of Neurophysiological Markers.科萨科夫综合征探索的新视角:神经生理学标志物的作用
Front Psychol. 2016 Feb 16;7:168. doi: 10.3389/fpsyg.2016.00168. eCollection 2016.
2
Brain-stem auditory evoked potentials in multiple sclerosis: the relation to VEP, SEP and CSF immunoglobulins.多发性硬化症中的脑干听觉诱发电位:与视觉诱发电位、体感诱发电位及脑脊液免疫球蛋白的关系。
J Neurol. 1990 Oct;237(6):376-8. doi: 10.1007/BF00315663.