Department of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Sci Rep. 2021 Jul 15;11(1):14568. doi: 10.1038/s41598-021-94062-2.
Acceleromyography at the adductor pollicis located in a distal part of the body may not reflect the degree of neuromuscular blockade (NMB) at the proximally located muscles manipulated during lumbar surgery. We investigated the usefulness and characteristics of acceleromyographic monitoring at the trapezius for providing moderate NMB during lumbar surgery. Fifty patients were randomized to maintain a train-of-four count 1-3 using acceleromyography at the adductor pollicis (group A; n = 25) or the trapezius (group T; n = 25). Total rocuronium dose administered intraoperatively [mean ± SD, 106.4 ± 31.3 vs. 74.1 ± 17.6 mg; P < 0.001] and surgical satisfaction (median [IQR], 7 [5-8] vs. 5 [4-5]; P < 0.001) were significantly higher in group T than group A. Lumbar retractor pressure (88.9 ± 12.0 vs. 98.0 ± 7.8 mmHg; P = 0.003) and lumbar muscle tone in group T were significantly lower than group A. Time to maximum block with an intubating dose was significantly shorter in group T than group A (44 [37-54] vs. 60 [55-65] sec; P < 0.001). Other outcomes were comparable. Acceleromyography at the trapezius muscle during lumbar surgery required a higher rocuronium dose for moderate NMB than the adductor pollicis muscle, thereby the consequent deeper NMB provided better surgical conditions. Trapezius as proximal muscle may better reflect surgical conditions of spine muscle.
在身体的远端部位的拇内收肌进行加速肌电图可能无法反映在腰椎手术中操作的近端肌肉的神经肌肉阻滞(NMB)程度。我们研究了在腰椎手术期间使用加速肌电图监测斜方肌提供中度 NMB 的有用性和特征。50 名患者被随机分为两组,使用拇内收肌的加速肌电图(A 组,n=25)或斜方肌的加速肌电图(T 组,n=25)来维持四串计数 1-3。术中给予的罗库溴铵总剂量(平均值±标准差,106.4±31.3 与 74.1±17.6 mg;P<0.001)和手术满意度(中位数[IQR],7[5-8]与 5[4-5];P<0.001)在 T 组明显高于 A 组。T 组的腰椎牵开器压力(88.9±12.0 与 98.0±7.8 mmHg;P=0.003)和腰椎肌肉张力明显低于 A 组。T 组达到插管剂量的最大阻滞时间明显短于 A 组(44[37-54]与 60[55-65]秒;P<0.001)。其他结果相当。在腰椎手术期间,与拇内收肌相比,斜方肌的加速肌电图需要更高剂量的罗库溴铵来实现中度 NMB,从而提供更好的手术条件。作为近端肌肉的斜方肌可能更好地反映脊柱肌肉的手术条件。