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化疗后对一名6个月大的肝母细胞瘤患儿进行中央肝切除术

Central Hepatectomy in a 6-Month-Old Child with Hepatoblastoma following Chemotherapy.

作者信息

Ho Huu Thien, Mai Trung Hieu, Nguyen Thanh Xuan, Nguyen Kim Hoa Thi, Pham Nhu Hien, Nguyen Huu Son

机构信息

Department of Abdominal Emergency and Pediatric Surgery, Hue Central Hospital, Hue City, Vietnam.

Pediatric Center, Hue Central Hospital, Hue City, Vietnam.

出版信息

Case Rep Oncol. 2021 Jun 17;14(2):874-880. doi: 10.1159/000516800. eCollection 2021 May-Aug.

DOI:10.1159/000516800
PMID:34267635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8261264/
Abstract

A hepatoblastoma in a 6-month-old child was initially considered unresectable because of diffuse liver involvement. The patient received 4 courses of cisplatin with an interval time of 2 weeks. A computed tomography scan after 4 courses of chemotherapy showed shrinking of the tumor, which made it resectable, and the tumor was removed by central hepatectomy. The patient was able to eat a regular diet on the fourth day and was sent home on the seventh day, after the operation. The pediatric oncologist followed the patient with liver ultrasonography and alpha-fetoprotein and administered 2 more cycles of cisplatin.

摘要

一名6个月大儿童的肝母细胞瘤最初因肝脏弥漫性受累而被认为无法切除。该患者接受了4个疗程的顺铂治疗，间隔时间为2周。4个疗程化疗后的计算机断层扫描显示肿瘤缩小，使其能够被切除，随后通过肝中央切除术将肿瘤切除。患者术后第四天能够正常饮食，第七天出院。儿科肿瘤学家通过肝脏超声检查和甲胎蛋白对患者进行随访，并又给予了2个周期的顺铂治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/96d15f796f91/cro-0014-0874-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/adf836cf0f13/cro-0014-0874-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/2ac3599f5be3/cro-0014-0874-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/e2926384c9f9/cro-0014-0874-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/45f79fa6b5eb/cro-0014-0874-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/9f2c15cc06d6/cro-0014-0874-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/07fb67247a40/cro-0014-0874-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/96d15f796f91/cro-0014-0874-g07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/adf836cf0f13/cro-0014-0874-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/2ac3599f5be3/cro-0014-0874-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/e2926384c9f9/cro-0014-0874-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/45f79fa6b5eb/cro-0014-0874-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/9f2c15cc06d6/cro-0014-0874-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/07fb67247a40/cro-0014-0874-g06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3dd/8261264/96d15f796f91/cro-0014-0874-g07.jpg

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本文引用的文献

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Outcomes of children with hepatoblastoma who underwent liver resection at a tertiary hospital in China: a retrospective analysis.中国一家三级医院行肝切除术治疗肝母细胞瘤患儿的结局：一项回顾性分析。
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Complete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the Children's Oncology Group.对于具有纯胎儿组织学特征的肝母细胞瘤患儿，完整的手术切除是治愈的关键：来自儿童肿瘤协作组的报告。
J Clin Oncol. 2011 Aug 20;29(24):3301-6. doi: 10.1200/JCO.2010.29.3837. Epub 2011 Jul 18.
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Outcome of central hepatectomy for hepatoblastomas.肝母细胞瘤中央切除术的结果。
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