Proctor Enola K, McKay Virginia R, Toker Emre, Maddox Thomas M, Hooley Cole, Lengnick-Hall Rebecca, MacGibbon Simon, Evanoff Bradley
Brown School, Washington University in St. Louis, Saint Louis, MO, USA.
Washington University Medical School in St. Louis, Saint Louis, MO, USA.
J Clin Transl Sci. 2021 Apr 8;5(1):e121. doi: 10.1017/cts.2021.778. eCollection 2021.
Understanding how to translate research discoveries into solutions for healthcare improvement is a priority of NIH-funded Clinical and Translational Science Awards (CTSA). This study, supported by one CTSA, aims to capture one process of shaping and implementing innovations to advance the timeliness and patient-centeredness of cardiovascular care. Specifically, we sought to understand a partnership between a private digital health startup company, a university innovation lab, and an academic health system's cardiology program pursuing this goal.
The collaboration proceeded through clear phases to address the questions and challenges: problem definition, exploration and formalization of the partnership, innovation co-creation and pilot test, and scale-up planning. Phases were punctuated by key decisions, such as forming the partnership, negotiating terms of the partnership, iterating form and features of the innovation, and exploring sufficiency of its value-add for scale-up and sustainment. Key implementation concepts were apparent, including implementation strategies (e.g., champions and iterative trialing) and the implementation outcomes of acceptability, sustainment, and scale-up. Participants identified potential risks of collaboration, reflected on their co-creation process, and the value of engaging stakeholders in innovation design. Findings may inform subsequent collaborations between innovators and translational researchers.
We conducted a case study to understand the partnership; characterize the questions they pursued, their decision points, information and data sources; and identify the challenges and risks. Data were collected through a series of four focus groups with members of each partnering organization. A transdisciplinary research team iteratively worked to condense and synthesize data from audio recorded transcripts into a case narrative.
了解如何将研究成果转化为改善医疗保健的解决方案是美国国立卫生研究院资助的临床与转化科学奖(CTSA)的一项优先任务。本研究由一项CTSA资助,旨在捕捉塑造和实施创新以提高心血管护理及时性和以患者为中心程度的一个过程。具体而言,我们试图了解一家私营数字健康初创公司、一个大学创新实验室以及一个学术健康系统的心脏病学项目之间为实现这一目标而建立的合作关系。
合作按明确的阶段进行,以解决相关问题和挑战:问题定义、伙伴关系的探索与正式确立、创新共创与试点测试以及扩大规模规划。各阶段以关键决策为标志,例如建立伙伴关系、协商伙伴关系条款、迭代创新的形式和功能,以及探索其扩大规模和维持所需的附加值是否充足。关键的实施概念很明显,包括实施策略(如倡导者和迭代试验)以及可接受性、可持续性和扩大规模等实施成果。参与者识别了合作的潜在风险,反思了他们的共创过程,以及让利益相关者参与创新设计的价值。研究结果可能为创新者和转化研究人员之间的后续合作提供参考。
我们进行了一项案例研究,以了解这种合作关系;描述他们所追求的问题、决策点、信息和数据来源;并识别挑战和风险。通过与每个合作组织的成员进行一系列四个焦点小组讨论来收集数据。一个跨学科研究团队反复努力,将录音转录本中的数据浓缩并综合成一个案例叙述。