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一种用于 1.5T 下超高极化氙肺磁共振成像的非对称全身鸟笼射频线圈,无射频屏蔽。

An asymmetrical whole-body birdcage RF coil without RF shield for hyperpolarized Xe lung MR imaging at 1.5 T.

机构信息

POLARIS, Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.

Department of Medical Physics, Cross Cancer Institute and University of Alberta, Alberta, Canada.

出版信息

Magn Reson Med. 2021 Dec;86(6):3373-3381. doi: 10.1002/mrm.28915. Epub 2021 Jul 15.

Abstract

PURPOSE

This study describes the development and testing of an asymmetrical xenon-129 ( Xe) birdcage radiofrequency (RF) coil for Xe lung ventilation imaging at 1.5 Tesla, which allows proton ( H) system body coil transmit-receive functionality.

METHODS

The Xe RF coil is a whole-body asymmetrical elliptical birdcage constructed without an outer RF shield to enable H imaging. field homogeneity and flip angle mapping of the Xe birdcage RF coil and H system body RF coil with the Xe RF coil in situ were evaluated in the MR scanner. The functionality of the Xe birdcage RF coil was demonstrated through hyperpolarized Xe lung ventilation imaging with the birdcage in both transceiver configuration and transmit-only configuration when combined with an 8-channel Xe receive-only RF coil array. The functionality of H system body coil with the Xe RF coil in situ was demonstrated by acquiring coregistered H lung anatomical MR images.

RESULTS

The asymmetrical birdcage produced a homogeneous field (±10%) in agreement with electromagnetic simulations. Simulations indicated an optimal detuning configuration with 4 diodes. The obtained g-factor of 1.4 for acceleration factor of R = 2 indicates optimal array configuration. Coregistered H anatomical images from the system body coil along with Xe lung images demonstrated concurrent and compatible arrangement of the RF coils.

CONCLUSION

A large asymmetrical birdcage for homogenous transmission with high sensitivity reception for Xe lung MRI at 1.5 Tesla has been demonstrated. The unshielded asymmetrical birdcage design enables H structural lung MR imaging in the same exam.

摘要

目的

本研究描述了一种用于 1.5T 下氙-129(Xe)肺部通气成像的非对称 Xe 笼状射频(RF)线圈的开发和测试,该线圈允许质子(H)系统体线圈进行发射-接收功能。

方法

Xe RF 线圈是一种整体非对称的椭圆形鸟笼结构,没有外部 RF 屏蔽,以实现 H 成像。在磁共振扫描仪中,评估了 Xe 鸟笼 RF 线圈和 H 系统体 RF 线圈的磁场均匀性和翻转角映射,并在原位使用 Xe RF 线圈。通过使用收发配置和仅发射配置下的鸟笼进行 hyperpolarized Xe 肺部通气成像,证明了 Xe 鸟笼 RF 线圈的功能,当与 8 通道 Xe 仅接收 RF 线圈阵列结合使用时。通过原位使用 Xe RF 线圈获取配准的 H 肺部解剖学 MR 图像,证明了 H 系统体线圈的功能。

结果

非对称鸟笼产生了均匀的磁场(±10%),与电磁模拟结果一致。模拟表明,具有 4 个二极管的最佳调谐配置。获得的 R = 2 的加速度因子 g 因子为 1.4,表明了最佳的阵列配置。来自系统体线圈的配准的 H 解剖图像以及 Xe 肺部图像表明了 RF 线圈的同时和兼容布置。

结论

已经证明了一种用于 1.5T 下均匀传输和高灵敏度接收的大型非对称鸟笼,用于 Xe 肺部 MRI。无屏蔽的非对称鸟笼设计允许在同一检查中进行 H 结构肺部磁共振成像。

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