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川崎病休克综合征与 COVID-19。

Kawasaki Shock Syndrome and Covid-19.

机构信息

Department of Pediatrics, Liaquat National Hospital, Karachi, Pakistan.

出版信息

J Coll Physicians Surg Pak. 2021 Jul;31(7):135-137. doi: 10.29271/jcpsp.2021.Supp2.S135.

Abstract

Kawasaki disease (KD) is a systemic vasculitis of unknown cause affecting children under 5 years of age. It is thought to be triggered by several viruses. Recently, Kawasaki-like disease has been reported worldwide in patients with COVID-19, giving rise to a new term of multi-system inflammatory syndrome in children (MIS-C). We report a case of a previously healthy 7-year boy, referred to our hospital with provisional diagnosis of measles due to generalised erythematous, maculopapular rash and conjunctivitis. On detailed evaluation, the patient fulfilled the clinical and laboratory criteria of MIS-C, and COVID-19 antibodies were positive. He was treated successfully with high dose of intravenous immunoglobulins (IVIG) and methylprednisolone. Patient was followed one week later with repeat echocardiography, which showed improvement. In conclusion, early recognition and timely treatment can prevent adverse outcomes in MIS-C. Key Words: COVID-19, Kawasaki disease, MIS-C.

摘要

川崎病(KD)是一种病因不明的全身性血管炎,影响 5 岁以下儿童。据认为,它是由几种病毒引发的。最近,在 COVID-19 患者中,世界各地都有川崎病样疾病的报告,由此产生了一个新的术语:儿童多系统炎症综合征(MIS-C)。我们报告了一例先前健康的 7 岁男孩,因全身性红斑、斑丘疹和结膜炎,被转诊至我院,暂定诊断为麻疹。经过详细评估,该患者符合 MIS-C 的临床和实验室标准,且 COVID-19 抗体呈阳性。他成功地接受了大剂量静脉注射免疫球蛋白(IVIG)和甲基强的松龙治疗。一周后,患者再次接受超声心动图检查,显示有所改善。总之,早期识别和及时治疗可以预防 MIS-C 的不良后果。关键词:COVID-19、川崎病、MIS-C。

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