Department of Pathology, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Department of Pathology, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Clin Dermatol. 2021 Mar-Apr;39(2):194-198. doi: 10.1016/j.clindermatol.2020.10.013. Epub 2020 Oct 16.
Necrotizing infundibular crystalline folliculitis is a rare condition characterized by folliculocentric waxy papules in the seborrheic areas of adult patients, with intrafollicular filamentous birefringent crystalline deposits as the histopathologic clue. Although the real pathogenesis of necrotizing infundibular crystalline folliculitis remains unclear, the intrafollicular material seems to be derived from an interaction between such superficial microorganisms as gram-positive bacteria (Propionibacterium acnes, Staphylococcus spp), Malassezia yeasts, and sebaceous lipids. Topical or systemic antiacne agents or antimycotics appear to be effective therapy.
化脓性汗管囊状炎是一种罕见的疾病，其特征为成年患者皮脂溢出部位出现毛囊中心性蜡样丘疹，组织病理学线索为毛囊内丝状双折射结晶沉积。虽然化脓性汗管囊状炎的确切发病机制尚不清楚，但毛囊内物质似乎来源于痤疮丙酸杆菌（丙酸杆菌、葡萄球菌属）、马拉色菌酵母和皮脂脂质等浅表微生物的相互作用。局部或全身用抗痤疮药或抗真菌药似乎是有效的治疗方法。
