Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, Hakodate, Japan.
Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Thorac Cancer. 2021 Sep;12(17):2407-2410. doi: 10.1111/1759-7714.14084. Epub 2021 Jul 17.
Pseudocirrhosis is a radiological diagnosis of cirrhosis without histological evidence and occurs as a complication of liver metastases from solid tumors. A 50-year-old man without any previous history of liver disease was diagnosed with adenocarcinoma of the left upper lung lobe and liver metastasis. After chemotherapy, the liver metastases shrank; however, over time, the liver shrank and showed cirrhosis-like morphological changes. His performance status deteriorated due to ascites and leg edema, and chemotherapy was terminated. Physicians treating lung adenocarcinoma with liver metastases should be aware that pseudocirrhosis is a rare but important complication that can worsen performance status (PS) and hinder treatment continuation.
假小叶症是一种无组织学证据的肝硬化的影像学诊断，发生于实体瘤肝转移的并发症。一名 50 岁男性，无任何肝脏疾病既往史，被诊断为左肺上叶腺癌伴肝转移。化疗后，肝转移灶缩小；然而，随着时间的推移，肝脏缩小并呈现出类似肝硬化的形态学改变。由于腹水和腿部水肿，他的体能状态恶化，化疗也因此终止。治疗肺癌伴肝转移的医生应该意识到，假小叶症是一种罕见但重要的并发症，它会恶化体能状态（PS）并阻碍治疗的继续。
